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    Ppp1r18 protein phosphatase 1, regulatory subunit 18 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361790, updated on 10-Jul-2024

    Summary

    Official Symbol
    Ppp1r18provided by RGD
    Official Full Name
    protein phosphatase 1, regulatory subunit 18provided by RGD
    Primary source
    RGD:1309543
    See related
    EnsemblRapid:ENSRNOG00000071251 AllianceGenome:RGD:1309543
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Kiaa1949; RGD1309543
    Summary
    Predicted to enable phosphatase binding activity. Orthologous to human PPP1R18 (protein phosphatase 1 regulatory subunit 18). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Spleen (RPKM 92.8), Lung (RPKM 89.6) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ppp1r18 in Genome Data Viewer
    Location:
    20p12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (2882370..2892329, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (2877567..2887526, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (3372412..3397351, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene alpha tubulin acetyltransferase 1 Neighboring gene similar to human chromosome 6 open reading frame 136 Neighboring gene DEAH-box helicase 16 Neighboring gene microRNA 6328 Neighboring gene nurim Neighboring gene mediator of DNA damage checkpoint 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables phosphatase binding IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001126287.2NP_001119759.2  phostensin

      See identical proteins and their annotated locations for NP_001119759.2

      Status: VALIDATED

      Source sequence(s)
      BC161960
      UniProtKB/TrEMBL
      A6KT82, B1WC08, G3V629
      Related
      ENSRNOP00000098224.2, ENSRNOT00000120583.2
      Conserved Domains (2) summary
      pfam13914
      Location:430545
      Phostensin; Phostensin PP1-binding and SH3-binding region
      pfam13916
      Location:28116
      Phostensin_N; PP1-regulatory protein, Phostensin N-terminal

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      2882370..2892329 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)