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    Rbm33 RNA binding motif protein 33 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362297, updated on 13-Apr-2024

    Summary

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    Symbol
    Rbm33provided by RGD
    Full Name
    RNA binding motif protein 33provided by RGD
    Primary source
    RGD:1310651
    See related
    Ensembl:ENSRNOG00000006718 AllianceGenome:RGD:1310651
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310651
    Summary
    Predicted to enable nucleic acid binding activity. Orthologous to human RBM33 (RNA binding motif protein 33). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 134.7), Spleen (RPKM 107.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rbm33 in Genome Data Viewer
    Location:
    4q11
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (7714660..7825469, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (6980807..7088334, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (592616..700903)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene ataxin-8-like Neighboring gene uncharacterized LOC120102203 Neighboring gene uncharacterized LOC102546975 Neighboring gene uncharacterized LOC134486706 Neighboring gene sonic hedgehog signaling molecule Neighboring gene canopy FGF signaling regulator 1 Neighboring gene engrailed homeobox 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables N6-methyladenosine-containing RNA reader activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables lncRNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein-macromolecule adaptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA export from nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of mRNA stability ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    RNA-binding protein 33
    Names
    RNA-binding protein 33-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191859.1 → NP_001178788.1  RNA-binding protein 33

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      D3ZTA8
      Related
      ENSRNOP00000030808.4, ENSRNOT00000033377.5
      Conserved Domains (2) summary
      cd00590
      Location:1153 → 1218
      RRM_SF; RNA recognition motif (RRM) superfamily
      TIGR02794
      Location:798 → 877
      tolA_full; TolA protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      7714660..7825469 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006235845.5 → XP_006235907.1  RNA-binding protein 33 isoform X5

      UniProtKB/TrEMBL
      A0A8I6AN05
      Related
      ENSRNOP00000094894.1
      Conserved Domains (2) summary
      cd00590
      Location:1113 → 1178
      RRM_SF; RNA recognition motif (RRM) superfamily
      TIGR02794
      Location:758 → 837
      tolA_full; TolA protein

    2. XM_063286223.1 → XP_063142293.1  RNA-binding protein 33 isoform X3

    3. XM_017592681.3 → XP_017448170.1  RNA-binding protein 33 isoform X7

    4. XM_039107741.2 → XP_038963669.1  RNA-binding protein 33 isoform X4

      Conserved Domains (5) summary
      PHA03418
      Location:425 → 465
      PHA03418; hypothetical E4 protein; Provisional
      PHA03247
      Location:412 → 703
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:30 → 216
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      PRK09510
      Location:776 → 847
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd00590
      Location:1129 → 1194
      RRM_SF; RNA recognition motif (RRM) superfamily

    5. XM_017592680.3 → XP_017448169.1  RNA-binding protein 33 isoform X6

    6. XM_017592678.3 → XP_017448167.1  RNA-binding protein 33 isoform X2

    7. XM_017592677.3 → XP_017448166.1  RNA-binding protein 33 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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