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    Diras1 DIRAS family GTPase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 366826, updated on 14-Nov-2024

    Summary

    Official Symbol
    Diras1provided by RGD
    Official Full Name
    DIRAS family GTPase 1provided by RGD
    Primary source
    RGD:1310445
    See related
    EnsemblRapid:ENSRNOG00000029738 AllianceGenome:RGD:1310445
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in signal transduction. Predicted to be active in plasma membrane. Orthologous to human DIRAS1 (DIRAS family GTPase 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 64.1) See more
    Orthologs
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    Genomic context

    See Diras1 in Genome Data Viewer
    Location:
    7q11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (9338660..9343524)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (8687964..8692828)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (11556192..11561056)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 39 member 3 Neighboring gene uncharacterized LOC120093772 Neighboring gene G protein subunit gamma 7 Neighboring gene uncharacterized LOC102553301 Neighboring gene transfer RNA proline (anticodon AGG) 48

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GDP binding  
    enables GTP binding  
    enables GTP binding  
    enables GTPase activity  
    enables GTPase activity  
    NOT enables mitogen-activated protein kinase binding  
    Component Evidence Code Pubs
    located_in endomembrane system  
    is_active_in plasma membrane  
    located_in plasma membrane  

    General protein information

    Preferred Names
    GTP-binding protein Di-Ras1
    Names
    DIRAS family, GTP-binding RAS-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108987.1NP_001102457.1  GTP-binding protein Di-Ras1

      See identical proteins and their annotated locations for NP_001102457.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474029
      UniProtKB/TrEMBL
      A6K8D5, D4A304
      Related
      ENSRNOP00000110380.1, ENSRNOT00000173126.1
      Conserved Domains (1) summary
      cl38936
      Location:7168
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      9338660..9343524
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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