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    Nxpe4 neurexophilin and PC-esterase domain family member 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500991, updated on 2-Nov-2024

    Summary

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    Symbol
    Nxpe4provided by RGD
    Full Name
    neurexophilin and PC-esterase domain family member 4provided by RGD
    Primary source
    RGD:1560781
    See related
    EnsemblRapid:ENSRNOG00000070472 AllianceGenome:RGD:1560781
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam55b; Fam55d
    Summary
    Predicted to be located in extracellular region. Orthologous to human NXPE4 (neurexophilin and PC-esterase domain family member 4). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Liver (RPKM 754.3), Spleen (RPKM 84.6) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Nxpe4 in Genome Data Viewer
    Location:
    8q23
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (57399199..57640629)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (48502697..48744101)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (52717341..52734448)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094370 Neighboring gene uncharacterized LOC134480045 Neighboring gene neurexophilin and PC-esterase domain family, member 2 Neighboring gene neurexophilin and PC-esterase domain family, member 1 Neighboring gene RNA exonuclease 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Gonzalez-Begne M, et al. J Proteome Res, 2009 Mar. PMID 19199708, Free PMC Article
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    NXPE family member 4
    Names
    family with sequence similarity 55, member B
    protein FAM55D

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025055.1 → NP_001020226.1  NXPE family member 4 precursor

      See identical proteins and their annotated locations for NP_001020226.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083798
      UniProtKB/Swiss-Prot
      Q5XI89
      UniProtKB/TrEMBL
      A0A8I6AKA8
      Conserved Domains (1) summary
      pfam06312
      Location:127 → 255
      Neurexophilin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      57399199..57640629
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039081953.2 → XP_038937881.1  NXPE family member 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XI89
      UniProtKB/TrEMBL
      A0A8I6AKA8
      Conserved Domains (1) summary
      pfam06312
      Location:127 → 255
      Neurexophilin

    2. XM_063265980.1 → XP_063122050.1  NXPE family member 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XI89

    3. XM_063265984.1 → XP_063122054.1  NXPE family member 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XI89

    4. XM_039081950.2 → XP_038937878.1  NXPE family member 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XI89
      UniProtKB/TrEMBL
      A0A8I6AKA8
      Related
      ENSRNOP00000077636.2, ENSRNOT00000093967.2
      Conserved Domains (1) summary
      pfam06312
      Location:127 → 255
      Neurexophilin

    5. XM_039081947.2 → XP_038937875.1  NXPE family member 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XI89
      UniProtKB/TrEMBL
      A0A8I6AKA8
      Conserved Domains (1) summary
      pfam06312
      Location:127 → 255
      Neurexophilin

    6. XM_039081951.2 → XP_038937879.1  NXPE family member 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XI89
      UniProtKB/TrEMBL
      A0A8I6AKA8
      Conserved Domains (1) summary
      pfam06312
      Location:127 → 255
      Neurexophilin

    7. XM_063265981.1 → XP_063122051.1  NXPE family member 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XI89

    8. XM_039081948.2 → XP_038937876.1  NXPE family member 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XI89
      UniProtKB/TrEMBL
      A0A8I6AKA8
      Conserved Domains (1) summary
      pfam06312
      Location:127 → 255
      Neurexophilin

    9. XM_063265983.1 → XP_063122053.1  NXPE family member 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XI89

    10. XM_063265978.1 → XP_063122048.1  NXPE family member 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XI89

    11. XM_063265982.1 → XP_063122052.1  NXPE family member 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XI89

    12. XM_063265977.1 → XP_063122047.1  NXPE family member 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XI89

    13. XM_039081952.2 → XP_038937880.1  NXPE family member 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XI89
      UniProtKB/TrEMBL
      A0A8I6AKA8
      Conserved Domains (1) summary
      pfam06312
      Location:127 → 255
      Neurexophilin

    14. XM_063265985.1 → XP_063122055.1  NXPE family member 4 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XI89.1 GenPept UniProtKB/Swiss-Prot:Q5XI89

    Gene LinkOut

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