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    Sntg2 syntrophin, gamma 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298936, updated on 17-Aug-2024

    Summary

    Official Symbol
    Sntg2provided by RGD
    Official Full Name
    syntrophin, gamma 2provided by RGD
    Primary source
    RGD:1311276
    See related
    EnsemblRapid:ENSRNOG00000004928 AllianceGenome:RGD:1311276
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable PDZ domain binding activity and neuroligin family protein binding activity. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of dystrophin-associated glycoprotein complex. Orthologous to human SNTG2 (syntrophin gamma 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 14.0), Lung (RPKM 13.7) and 4 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Sntg2 in Genome Data Viewer
    Location:
    6q16
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (52529481..52730972, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (46801893..47003390, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (49123084..49324530, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene peroxidasin Neighboring gene thyroid peroxidase Neighboring gene uncharacterized LOC134479357 Neighboring gene uncharacterized LOC134479358 Neighboring gene peroxiredoxin 1, pseudogene 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables PDZ domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables neuroligin family protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    part_of dystrophin-associated glycoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in intracellular anatomical structure IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106720.2NP_001100190.1  gamma-2-syntrophin isoform 3

      See identical proteins and their annotated locations for NP_001100190.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A6HB30, D3ZR12
      Related
      ENSRNOP00000060286.1, ENSRNOT00000066904.3
    2. NM_001414914.1NP_001401843.1  gamma-2-syntrophin isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A8I6A197
      Related
      ENSRNOP00000085255.1, ENSRNOT00000097206.2
    3. NM_001414915.1NP_001401844.1  gamma-2-syntrophin isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      Related
      ENSRNOP00000105115.1, ENSRNOT00000172283.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      52529481..52730972 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039111960.2XP_038967888.1  gamma-2-syntrophin isoform X1