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    RGD1306474 similar to RIKEN cDNA 9530003J23 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362881, updated on 11-Apr-2024

    Summary

    Official Symbol
    RGD1306474provided by RGD
    Official Full Name
    similar to RIKEN cDNA 9530003J23provided by RGD
    Primary source
    RGD:1306474
    See related
    Ensembl:ENSRNOG00000005790 AllianceGenome:RGD:1306474
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Lyzf1
    Summary
    Predicted to enable lysozyme activity. Predicted to be involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Human ortholog(s) of this gene implicated in familial visceral amyloidosis. Orthologous to human LYZ (lysozyme). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Liver (RPKM 4.3) and Thymus (RPKM 0.4) See more
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    Genomic context

    See RGD1306474 in Genome Data Viewer
    Location:
    7q22
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (54761063..54772664, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (52875842..52880716, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (60305006..60309878, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L47, pseudogene 1 Neighboring gene YEATS domain containing 4 Neighboring gene lysozyme C type 2 Neighboring gene lysozyme 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables lysozyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in defense response to Gram-positive bacterium IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in killing of cells of another organism IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein LOC362881
    Names
    lysozyme f1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108746.1NP_001102216.1  uncharacterized protein LOC362881 precursor

      See identical proteins and their annotated locations for NP_001102216.1

      Status: PREDICTED

      Source sequence(s)
      CH473960
      UniProtKB/TrEMBL
      A6IGS1, D4A0W2
      Related
      ENSRNOP00000007610.4, ENSRNOT00000007610.5
      Conserved Domains (1) summary
      smart00263
      Location:22149
      LYZ1; Alpha-lactalbumin / lysozyme C

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      54761063..54772664 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063263797.1XP_063119867.1  uncharacterized protein LOC362881 isoform X1