Mtmr9 myotubularin related protein 9 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Mtmr9provided by RGD
Official Full Name: myotubularin related protein 9provided by RGD
Primary source: RGD:628840
See related: EnsemblRapid:ENSRNOG00000011560 AllianceGenome:RGD:628840
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable enzyme regulator activity; phosphatidylinositol-3-phosphatase activity; and protein phosphatase binding activity. Predicted to be involved in several processes, including phosphatidylinositol dephosphorylation; protein stabilization; and regulation of dephosphorylation. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and membrane. Orthologous to human MTMR9 (myotubularin related protein 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Brain (RPKM 179.7), Heart (RPKM 108.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 15p12

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	15	NC_086033.1 (41945102..41967136, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	15	NC_051350.1 (37769161..37791195, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	15	NC_005114.4 (46697262..46719296, complement)

Chromosome 15 - NC_086033.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables enzyme regulator activity	ISO Inferred from Sequence Orthology more info
enables protein phosphatase binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein phosphatase binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in negative regulation of autophagy	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of autophagy	ISO Inferred from Sequence Orthology more info
involved_in phosphatidylinositol dephosphorylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of phosphatase activity	ISO Inferred from Sequence Orthology more info
involved_in protein stabilization	ISO Inferred from Sequence Orthology more info
involved_in regulation of phosphatidylinositol dephosphorylation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: myotubularin-related protein 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001005761.1 → NP_001005761.1 myotubularin-related protein 9

See identical proteins and their annotated locations for NP_001005761.1

Status: PROVISIONAL

Source sequence(s)

BC083644

UniProtKB/TrEMBL

A6K6G4, F7F3L9, Q5XIN4, Q8K3W5

Related

ENSRNOP00000015452.4, ENSRNOT00000015452.7

Conserved Domains (2) summary

cd13211
Location:1 → 97

PH-GRAM_MTMR9; Myotubularian (MTM) related 9 protein (MTMR9) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain

pfam06602
Location:121 → 446

Myotub-related; Myotubularin-like phosphatase domain