Lrrc10 leucine-rich repeat-containing 10 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Lrrc10provided by RGD
Full Name: leucine-rich repeat-containing 10provided by RGD
Primary source: RGD:1307358
See related: Ensembl:ENSRNOG00000005555 AllianceGenome:RGD:1307358
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable actin binding activity and alpha-actinin binding activity. Predicted to be involved in cardiac muscle cell development. Predicted to be located in mitochondrion; myofibril; and nucleus. Predicted to be active in cytoskeleton and sarcomere. Orthologous to human LRRC10 (leucine rich repeat containing 10). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: 7q22

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (54572935..54574332)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (52686972..52688369)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (60087361..60088758)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

RH134602 (e-PCR)
- UniSTS:217882

UniSTS:471082 (e-PCR)
- UniSTS:471082

Lrrc10 (e-PCR), detects polymorphism
- UniSTS:471082

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables actin binding	IBA Inferred from Biological aspect of Ancestor more info
enables actin binding	ISO Inferred from Sequence Orthology more info
enables alpha-actinin binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cardiac muscle cell development	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cardiac muscle cell development	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoskeleton	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in myofibril	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
is_active_in sarcomere	IBA Inferred from Biological aspect of Ancestor more info
located_in sarcomere	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: leucine-rich repeat-containing protein 10

Names: leucine-rich repeat-containing protein 10-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001108096.1 → NP_001101566.1 leucine-rich repeat-containing protein 10

See identical proteins and their annotated locations for NP_001101566.1

Status: PROVISIONAL

Source sequence(s)

CH473960

UniProtKB/TrEMBL

A6IGR3, D4AAU8

Related

ENSRNOP00000007338.2, ENSRNOT00000007338.4

Conserved Domains (3) summary

cd00116
Location:88 → 200

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

sd00033
Location:32 → 53

LRR_RI; leucine-rich repeat [structural motif]

pfam13855
Location:52 → 110

LRR_8; Leucine rich repeat