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    Txlna taxilin alpha [ Rattus norvegicus (Norway rat) ]

    Gene ID: 682457, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Txlnaprovided by RGD
    Official Full Name
    taxilin alphaprovided by RGD
    Primary source
    RGD:1583435
    See related
    EnsemblRapid:ENSRNOG00000048242 AllianceGenome:RGD:1583435
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable syntaxin binding activity. Predicted to act upstream of or within B cell activation. Predicted to be located in cytoplasm. Orthologous to human TXLNA (taxilin alpha). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 199.5), Spleen (RPKM 154.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Txlna in Genome Data Viewer
    Location:
    5q36
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (147253694..147269410, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (141969337..141985054, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (147830514..147846193, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108351039 Neighboring gene IQ motif containing C Neighboring gene coiled coil domain containing 28B Neighboring gene karyopherin subunit alpha 6 Neighboring gene transmembrane protein 39b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Developmental and spatial expression pattern of alpha-taxilin in the rat central nervous system. Sakakibara S, et al. J Comp Neurol, 2008 Nov 1. PMID 18729150
    2. Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis. Chu CC, et al. Mol Immunol, 1998 Jun. PMID 9798653
    3. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC187972

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables syntaxin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within B cell activation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    alpha-taxilin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127633.1 → NP_001121105.1  alpha-taxilin

      See identical proteins and their annotated locations for NP_001121105.1

      Status: PROVISIONAL

      Source sequence(s)
      BC166486
      UniProtKB/TrEMBL
      B2GV14
      Related
      ENSRNOP00000064617.1, ENSRNOT00000072165.3
      Conserved Domains (2) summary
      PHA03185
      Location:507 → 556
      PHA03185; UL14 tegument protein; Provisional
      pfam09728
      Location:171 → 478
      Taxilin; Myosin-like coiled-coil protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      147253694..147269410 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006238972.5 → XP_006239034.1  alpha-taxilin isoform X1

      See identical proteins and their annotated locations for XP_006239034.1

      UniProtKB/TrEMBL
      B2GV14
      Conserved Domains (2) summary
      PHA03185
      Location:507 → 556
      PHA03185; UL14 tegument protein; Provisional
      pfam09728
      Location:171 → 478
      Taxilin; Myosin-like coiled-coil protein
    Nucleotide Protein Strain
    Heading Accession and Version

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