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    Zfp322a zinc finger protein 322a [ Rattus norvegicus (Norway rat) ]

    Gene ID: 680201, updated on 28-Oct-2024

    Summary

    Official Symbol
    Zfp322aprovided by RGD
    Official Full Name
    zinc finger protein 322aprovided by RGD
    Primary source
    RGD:1594230
    See related
    EnsemblRapid:ENSRNOG00000017318 AllianceGenome:RGD:1594230
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of stem cell population maintenance and regulation of transcription by RNA polymerase II. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human ZNF322 (zinc finger protein 322). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Biased expression in Adrenal (RPKM 124.6), Brain (RPKM 61.6) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Zfp322a in Genome Data Viewer
    Location:
    17p11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (42201989..42216060)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (41773789..41789654)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (44025036..44040900)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108348562 Neighboring gene small ribosomal subunit protein uS14-like Neighboring gene transfer RNA serine (anticodon ACU) Neighboring gene transfer RNA methionine (anticodon CAU) 6 Neighboring gene transfer RNA isoleucine (anticodon AAU) 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in positive regulation of stem cell population maintenance ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135084.1NP_001128556.1  zinc finger protein 322

      See identical proteins and their annotated locations for NP_001128556.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A0A8I5Y159, A6KLQ9, D3ZJ04
      Related
      ENSRNOP00000060068.1, ENSRNOT00000023268.7
      Conserved Domains (3) summary
      COG5048
      Location:68218
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:128148
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:168192
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      42201989..42216060
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063276732.1XP_063132802.1  zinc finger protein 322 isoform X1

      UniProtKB/TrEMBL
      A6KLQ9, D3ZJ04
      Related
      ENSRNOP00000111273.1, ENSRNOT00000135935.1
    2. XM_006253974.3XP_006254036.1  zinc finger protein 322 isoform X1

      See identical proteins and their annotated locations for XP_006254036.1

      UniProtKB/TrEMBL
      A0A8I5Y159, A6KLQ9, D3ZJ04
      Related
      ENSRNOP00000110848.1, ENSRNOT00000146695.1
      Conserved Domains (3) summary
      COG5048
      Location:68218
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:128148
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:168192
      zf-H2C2_2; Zinc-finger double domain
    3. XM_063276731.1XP_063132801.1  zinc finger protein 322 isoform X1

      UniProtKB/TrEMBL
      A6KLQ9, D3ZJ04
      Related
      ENSRNOP00000100976.1, ENSRNOT00000169148.1
    4. XM_063276733.1XP_063132803.1  zinc finger protein 322 isoform X1

      UniProtKB/TrEMBL
      A6KLQ9, D3ZJ04
      Related
      ENSRNOP00000111576.1, ENSRNOT00000142591.1