Zfp365 zinc finger protein 365 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Zfp365provided by RGD
Full Name: zinc finger protein 365provided by RGD
Primary source: RGD:1565986
See related: EnsemblRapid:ENSRNOG00000000638 AllianceGenome:RGD:1565986
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Znf365
Summary: Predicted to enable protein homodimerization activity. Involved in positive regulation of oligodendrocyte differentiation. Predicted to be located in centrosome and intracellular membrane-bounded organelle. Predicted to be active in centriolar satellite. Human ortholog(s) of this gene implicated in uric acid nephrolithiasis. Orthologous to human ZNF365 (zinc finger protein 365). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Brain (RPKM 255.9), Lung (RPKM 69.5) and 5 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 20p11

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	20	NC_086038.1 (20665122..20688607)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	20	NC_051355.1 (20666240..20689734)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	20	NC_005119.4 (22060160..22083766)

Chromosome 20 - NC_086038.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH137818 (e-PCR)
- UniSTS:219905

AU025826 (e-PCR)
- UniSTS:114882

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in cerebellar molecular layer morphogenesis	IEA Inferred from Electronic Annotation more info
involved_in cerebellar molecular layer morphogenesis	ISO Inferred from Sequence Orthology more info
involved_in cerebellar molecular layer morphogenesis	ISS Inferred from Sequence or Structural Similarity more info
involved_in dendrite arborization	IEA Inferred from Electronic Annotation more info
involved_in dendrite arborization	ISO Inferred from Sequence Orthology more info
involved_in dendrite arborization	ISS Inferred from Sequence or Structural Similarity more info
involved_in dendritic spine morphogenesis	IEA Inferred from Electronic Annotation more info
involved_in dendritic spine morphogenesis	ISO Inferred from Sequence Orthology more info
involved_in dendritic spine morphogenesis	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of neuron projection development	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of neuron projection development	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of oligodendrocyte differentiation	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of oligodendrocyte differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of oligodendrocyte differentiation	ISO Inferred from Sequence Orthology more info
involved_in regulation of DNA strand resection involved in replication fork processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of DNA strand resection involved in replication fork processing	IEA Inferred from Electronic Annotation more info
involved_in regulation of DNA strand resection involved in replication fork processing	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of double-strand break repair via homologous recombination	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of double-strand break repair via homologous recombination	IEA Inferred from Electronic Annotation more info
involved_in regulation of double-strand break repair via homologous recombination	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of neuron projection development	IBA Inferred from Biological aspect of Ancestor more info
involved_in telomere maintenance	IBA Inferred from Biological aspect of Ancestor more info
involved_in telomere maintenance	IEA Inferred from Electronic Annotation more info
involved_in telomere maintenance	ISO Inferred from Sequence Orthology more info
involved_in telomere maintenance	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in centrosome	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein ZNF365

Names: DISC1-binding zinc-finger protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.