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    Gtpbp6 GTP binding protein 6 (putative) [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363931, updated on 2-Nov-2024

    Summary

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    Symbol
    Gtpbp6provided by RGD
    Full Name
    GTP binding protein 6 (putative)provided by RGD
    Primary source
    RGD:1305954
    See related
    EnsemblRapid:ENSRNOG00000062521 AllianceGenome:RGD:1305954
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305954
    Summary
    Predicted to enable ribosome binding activity. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Orthologous to human GTPBP6 (GTP binding protein 6 (putative)). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Adrenal (RPKM 81.1), Muscle (RPKM 80.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Gtpbp6 in Genome Data Viewer
    Location:
    12q16
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (52234646..52238578)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (46574913..46578873)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (52637000..52640869)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene golgin A3 Neighboring gene uncharacterized LOC134481217 Neighboring gene checkpoint with forkhead and ring finger domains Neighboring gene zinc finger protein 605 Neighboring gene RIKEN cDNA B230307C23 gene like Neighboring gene phosphatidylinositol-specific phospholipase C, X domain containing 1 Neighboring gene zinc finger protein 950 like 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative GTP-binding protein 6
    Names
    putative GTP-binding protein 6-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135840.1 → NP_001129312.1  putative GTP-binding protein 6

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A0A8I5ZU18
      Related
      ENSRNOP00000080925.1, ENSRNOT00000105776.2
      Conserved Domains (4) summary
      cd01878
      Location:270 → 441
      HflX; HflX GTPase family
      COG2262
      Location:105 → 501
      HflX; 50S ribosomal subunit-associated GTPase HflX [Translation, ribosomal structure and biogenesis]
      pfam13167
      Location:109 → 195
      GTP-bdg_N; GTP-binding GTPase N-terminal
      pfam16360
      Location:199 → 255
      GTP-bdg_M; GTP-binding GTPase Middle Region

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      52234646..52238578
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063271566.1 → XP_063127636.1  putative GTP-binding protein 6 isoform X3

    2. XM_039089647.2 → XP_038945575.1  putative GTP-binding protein 6 isoform X2

    3. XM_039089646.2 → XP_038945574.1  putative GTP-binding protein 6 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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