Krt90 keratin 90 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Krt90provided by RGD
Official Full Name: keratin 90provided by RGD
Primary source: RGD:1565564
See related: EnsemblRapid:ENSRNOG00000009105 AllianceGenome:RGD:1565564
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Kb15
Summary: Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be active in keratin filament. Human ortholog(s) of this gene implicated in focal or diffuse nonepidermolytic palmoplantar keratoderma. Orthologous to human KRT6C (keratin 6C). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Biased expression in Thymus (RPKM 3.2), Testes (RPKM 0.8) and 5 other tissues See more
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Genomic context

Location:: 7q36

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (134555972..134565420, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (132677994..132686634, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (143208034..143217771, complement)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH135363 (e-PCR)
- UniSTS:218640

AI070206 (e-PCR)
- UniSTS:243691

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables structural constituent of skin epidermis	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in intermediate filament organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in keratinization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in keratin filament	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: keratin, type II cytoskeletal cochleal

Names: type II keratin Kb15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008825.1 → NP_001008825.1 keratin, type II cytoskeletal cochleal

See identical proteins and their annotated locations for NP_001008825.1

Status: PROVISIONAL

Source sequence(s)

BK003995

UniProtKB/TrEMBL

G3V908, Q6IFZ4

Conserved Domains (3) summary

pfam00038
Location:142 → 448

Filament; Intermediate filament protein

pfam16208
Location:16 → 139

Keratin_2_head; Keratin type II head

cl01888
Location:366 → 421

DUF883; Bacterial protein of unknown function (DUF883)