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    Gng11 G protein subunit gamma 11 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 64199, updated on 5-Mar-2024

    Summary

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    Symbol
    Gng11provided by RGD
    Full Name
    G protein subunit gamma 11provided by RGD
    Primary source
    RGD:621515
    See related
    Ensembl:ENSRNOG00000050469 AllianceGenome:RGD:621515
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Orthologous to human GNG11 (G protein subunit gamma 11). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Heart (RPKM 335.7), Lung (RPKM 227.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    4q13
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (32977681..32983121)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (32023003..32028443)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (28989170..28994610)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene tissue factor pathway inhibitor 2 Neighboring gene G protein subunit gamma transducin 1 Neighboring gene uncharacterized LOC108350669 Neighboring gene Bet1 golgi vesicular membrane trafficking protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits. Ray K, et al. J Biol Chem, 1995 Sep 15. PMID 7665596
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G-protein beta-subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of heterotrimeric G-protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
    Names
    guanine nucleotide binding protein (G protein), gamma 11
    guanine nucleotide binding protein gamma subunit 11
    guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022396.2 → NP_071791.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11

      See identical proteins and their annotated locations for NP_071791.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097320
      UniProtKB/Swiss-Prot
      P61954, Q4V8M0
      UniProtKB/TrEMBL
      A6K2B4
      Related
      ENSRNOP00000065818.1, ENSRNOT00000074048.2
      Conserved Domains (1) summary
      smart00224
      Location:12 → 73
      GGL; G protein gamma subunit-like motifs

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      32977681..32983121
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P61954.1 GenPept UniProtKB/Swiss-Prot:P61954

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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