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    ZNF571 zinc finger protein 571 [ Homo sapiens (human) ]

    Gene ID: 51276, updated on 2-Nov-2024

    Summary

    Official Symbol
    ZNF571provided by HGNC
    Official Full Name
    zinc finger protein 571provided by HGNC
    Primary source
    HGNC:HGNC:25000
    See related
    Ensembl:ENSG00000180479 AllianceGenome:HGNC:25000
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HSPC059
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in adrenal (RPKM 2.7), testis (RPKM 2.3) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See ZNF571 in Genome Data Viewer
    Location:
    19q13.12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (37564260..37594792, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (40366017..40396556, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (38055162..38085693, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ZNF793 antisense RNA 1 (head to head) Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:37996759-37997550 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:37997551-37998342 Neighboring gene zinc finger protein 793 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr19:38020876-38021698 Neighboring gene uncharacterized LOC124904708 Neighboring gene ZNF571 antisense RNA 1 Neighboring gene zinc finger protein 540 Neighboring gene MT-ND4 pseudogene 41 Neighboring gene MT-ND5 pseudogene 45 Neighboring gene MT-CO1 pseudogene 41 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:38084654-38085335 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:38085336-38086018 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14554 Neighboring gene ZFP30 zinc finger protein Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10556 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:38146535-38147522 Neighboring gene zinc finger protein 781

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ16374, MGC138690

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290314.2NP_001277243.1  zinc finger protein 571

      See identical proteins and their annotated locations for NP_001277243.1

      Status: VALIDATED

      Source sequence(s)
      AK291413, BC040591, BP312315
      Consensus CDS
      CCDS12505.1
      UniProtKB/Swiss-Prot
      Q2HIY0, Q3ZCU3, Q7Z3V5, Q9NZX7
      Related
      ENSP00000351594.3, ENST00000358744.3
      Conserved Domains (3) summary
      COG5048
      Location:193599
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:337357
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:546
      KRAB; KRAB box
    2. NM_001321272.2NP_001308201.1  zinc finger protein 571

      Status: VALIDATED

      Source sequence(s)
      AC022148, BC040591
      Consensus CDS
      CCDS12505.1
      UniProtKB/Swiss-Prot
      Q2HIY0, Q3ZCU3, Q7Z3V5, Q9NZX7
      Related
      ENSP00000467572.1, ENST00000593133.5
      Conserved Domains (3) summary
      COG5048
      Location:193599
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:337357
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:546
      KRAB; KRAB box
    3. NM_016536.5NP_057620.3  zinc finger protein 571

      See identical proteins and their annotated locations for NP_057620.3

      Status: VALIDATED

      Source sequence(s)
      AF161544, BC040591, BP312315
      Consensus CDS
      CCDS12505.1
      UniProtKB/Swiss-Prot
      Q2HIY0, Q3ZCU3, Q7Z3V5, Q9NZX7
      Related
      ENSP00000392638.1, ENST00000451802.7
      Conserved Domains (3) summary
      COG5048
      Location:193599
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:337357
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:546
      KRAB; KRAB box

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      37564260..37594792 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017026858.2XP_016882347.1  zinc finger protein 571 isoform X1

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      40366017..40396556 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054321162.1XP_054177137.1  zinc finger protein 571 isoform X1