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    Mrgpra4 MAS-related GPR, member A4 [ Mus musculus (house mouse) ]

    Gene ID: 235854, updated on 2-Nov-2024

    Summary

    Official Symbol
    Mrgpra4provided by MGI
    Official Full Name
    MAS-related GPR, member A4provided by MGI
    Primary source
    MGI:MGI:3033100
    See related
    Ensembl:ENSMUSG00000067173 AllianceGenome:MGI:3033100
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MrgA4; Mgrg10
    Summary
    Enables neuropeptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human MRGPRX4 (MAS related GPR family member X4). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See Mrgpra4 in Genome Data Viewer
    Location:
    7 B4; 7 31.08 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (47630542..47632044, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (47980794..47982296, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene MAS-related GPR, member A4 pseudogene Neighboring gene MAS-related GPR, member C2, pseudogene Neighboring gene MAS-related GPR, member X1 Neighboring gene MAS-related GPR, member B7, pseudogene

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables neuropeptide receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mas-related G-protein coupled receptor member A4
    Names
    Mas-related G protein-coupled receptor g10
    MrgA4 RF-amide G protein-coupled receptor
    RF-amide G-protein coupled receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153524.2NP_705744.2  mas-related G-protein coupled receptor member A4

      See identical proteins and their annotated locations for NP_705744.2

      Status: VALIDATED

      Source sequence(s)
      AY042194, BC115741
      Consensus CDS
      CCDS21298.1
      UniProtKB/Swiss-Prot
      Q1RLL1, Q91WW2
      UniProtKB/TrEMBL
      B7ZP12, W8W3F5
      Related
      ENSMUSP00000084327.3, ENSMUST00000087092.4
      Conserved Domains (1) summary
      pfam00001
      Location:38270
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      47630542..47632044 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)