U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PRR15L proline rich 15 like [ Homo sapiens (human) ]

    Gene ID: 79170, updated on 17-Sep-2024

    Summary

    Official Symbol
    PRR15Lprovided by HGNC
    Official Full Name
    proline rich 15 likeprovided by HGNC
    Primary source
    HGNC:HGNC:28149
    See related
    Ensembl:ENSG00000167183 AllianceGenome:HGNC:28149
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ATAD4
    Expression
    Biased expression in duodenum (RPKM 78.9), small intestine (RPKM 58.5) and 11 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See PRR15L in Genome Data Viewer
    Location:
    17q21.32
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (47951967..47957883, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (48813758..48819670, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (46029333..46035249, complement)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:45977450-45977954 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:45978459-45978962 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:45979467-45979970 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:45981458-45981651 Neighboring gene SP2 antisense RNA 1 Neighboring gene Sp2 transcription factor Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:46004735-46005236 Neighboring gene Sharpr-MPRA regulatory region 5948 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12320 Neighboring gene pyridoxamine 5'-phosphate oxidase Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:46033917-46034862 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:46034863-46035808 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8645 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:46048841-46049468 Neighboring gene CDK5 regulatory subunit associated protein 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:46052765-46053265 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:46072377-46072975 Neighboring gene Sharpr-MPRA regulatory region 8372 Neighboring gene uncharacterized LOC124904017 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12321

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Phenotypes

    EBI GWAS Catalog

    Description
    Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32
    EBI GWAS Catalog

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    proline-rich protein 15-like protein
    Names
    ATPase family, AAA domain containing 4
    testicular tissue protein Li 157

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024320.4NP_077296.1  proline-rich protein 15-like protein

      See identical proteins and their annotated locations for NP_077296.1

      Status: VALIDATED

      Source sequence(s)
      AA707319, AA916635, AC018521, BM829856, BM831136
      Consensus CDS
      CCDS11523.1
      UniProtKB/Swiss-Prot
      D3DTU0, Q9BU68
      UniProtKB/TrEMBL
      A0A140VJT1
      Related
      ENSP00000300557.2, ENST00000300557.3
      Conserved Domains (1) summary
      pfam15321
      Location:788
      ATAD4; ATPase family AAA domain containing 4

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      47951967..47957883 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005257663.5XP_005257720.1  proline-rich protein 15-like protein isoform X1

      See identical proteins and their annotated locations for XP_005257720.1

      UniProtKB/Swiss-Prot
      D3DTU0, Q9BU68
      UniProtKB/TrEMBL
      A0A140VJT1
      Conserved Domains (1) summary
      pfam15321
      Location:788
      ATAD4; ATPase family AAA domain containing 4
    2. XM_005257666.5XP_005257723.1  proline-rich protein 15-like protein isoform X1

      See identical proteins and their annotated locations for XP_005257723.1

      UniProtKB/Swiss-Prot
      D3DTU0, Q9BU68
      UniProtKB/TrEMBL
      A0A140VJT1
      Conserved Domains (1) summary
      pfam15321
      Location:788
      ATAD4; ATPase family AAA domain containing 4
    3. XM_047436740.1XP_047292696.1  proline-rich protein 15-like protein isoform X1

      UniProtKB/Swiss-Prot
      D3DTU0, Q9BU68
      UniProtKB/TrEMBL
      A0A140VJT1
    4. XM_005257664.2XP_005257721.1  proline-rich protein 15-like protein isoform X1

      See identical proteins and their annotated locations for XP_005257721.1

      UniProtKB/Swiss-Prot
      D3DTU0, Q9BU68
      UniProtKB/TrEMBL
      A0A140VJT1
      Conserved Domains (1) summary
      pfam15321
      Location:788
      ATAD4; ATPase family AAA domain containing 4
    5. XM_005257665.1XP_005257722.1  proline-rich protein 15-like protein isoform X1

      See identical proteins and their annotated locations for XP_005257722.1

      UniProtKB/Swiss-Prot
      D3DTU0, Q9BU68
      UniProtKB/TrEMBL
      A0A140VJT1
      Conserved Domains (1) summary
      pfam15321
      Location:788
      ATAD4; ATPase family AAA domain containing 4

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      48813758..48819670 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054317200.1XP_054173175.1  proline-rich protein 15-like protein isoform X1

      UniProtKB/Swiss-Prot
      D3DTU0, Q9BU68
      UniProtKB/TrEMBL
      A0A140VJT1
    2. XM_054317201.1XP_054173176.1  proline-rich protein 15-like protein isoform X1

      UniProtKB/Swiss-Prot
      D3DTU0, Q9BU68
      UniProtKB/TrEMBL
      A0A140VJT1
    3. XM_054317202.1XP_054173177.1  proline-rich protein 15-like protein isoform X1

      UniProtKB/Swiss-Prot
      D3DTU0, Q9BU68
      UniProtKB/TrEMBL
      A0A140VJT1
    4. XM_054317203.1XP_054173178.1  proline-rich protein 15-like protein isoform X1

      UniProtKB/Swiss-Prot
      D3DTU0, Q9BU68
      UniProtKB/TrEMBL
      A0A140VJT1
    5. XM_054317204.1XP_054173179.1  proline-rich protein 15-like protein isoform X1

      UniProtKB/Swiss-Prot
      D3DTU0, Q9BU68
      UniProtKB/TrEMBL
      A0A140VJT1