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    Kiaa1191 KIAA1191 homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306766, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Kiaa1191provided by RGD
    Official Full Name
    KIAA1191 homologprovided by RGD
    Primary source
    RGD:1359256
    See related
    EnsemblRapid:ENSRNOG00000017133 AllianceGenome:RGD:1359256
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Aa2-141; P33monox
    Summary
    Predicted to enable oxidoreductase activity. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Orthologous to human KIAA1191 (KIAA1191). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 1115.6), Heart (RPKM 316.9) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Kiaa1191 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (10054249..10066922)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (10049142..10061819)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (10586043..10598631)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene NOP16 nucleolar protein Neighboring gene ADP-ribosylation factor like GTPase 10 Neighboring gene SUMO-interacting motifs containing 1 Neighboring gene uncharacterized LOC134482678 Neighboring gene uncharacterized LOC134482679 Neighboring gene MAPK regulated co-repressor interacting protein 1 like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Characterizing the novel protein p33MONOX. Mishra M, et al. Mol Cell Biochem, 2011 Apr. PMID 21153684
    2. Identification and analysis of genes from the mouse otic vesicle and their association with developmental subprocesses through in situ hybridization. Powles N, et al. Dev Biol, 2004 Apr 1. PMID 15031102
    3. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC94694

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative monooxygenase p33MONOX
    Names
    liver regeneration-related protein LRRG011

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014007.4 → NP_001014029.1  putative monooxygenase p33MONOX isoform 1

      See identical proteins and their annotated locations for NP_001014029.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/Swiss-Prot
      Q5U2R6, Q7TP81
      UniProtKB/TrEMBL
      A0A8I6GIN5, A6KAZ0
      Conserved Domains (1) summary
      pfam15302
      Location:18 → 304
      P33MONOX; P33 mono-oxygenase

    2. NM_001419480.2 → NP_001406409.1  putative monooxygenase p33MONOX isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A6KAZ4

    3. NM_001419481.2 → NP_001406410.1  putative monooxygenase p33MONOX isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/Swiss-Prot
      Q5U2R6, Q7TP81
      UniProtKB/TrEMBL
      A6KAZ0
      Related
      ENSRNOP00000023125.8, ENSRNOT00000023125.9

    4. NM_001419482.2 → NP_001406411.1  putative monooxygenase p33MONOX isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A6KAZ4
      Related
      ENSRNOP00000090160.1, ENSRNOT00000104003.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      10054249..10066922
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039095632.2 → XP_038951560.1  putative monooxygenase p33MONOX isoform X3

      Conserved Domains (1) summary
      pfam15302
      Location:12 → 202
      P33MONOX; P33 mono-oxygenase

    2. XM_039095629.2 → XP_038951557.1  putative monooxygenase p33MONOX isoform X2

      UniProtKB/TrEMBL
      A0A8I6GIN5, A6KAZ4
      Conserved Domains (1) summary
      pfam15302
      Location:1 → 284
      P33MONOX; P33 mono-oxygenase

    3. XM_039095635.2 → XP_038951563.1  putative monooxygenase p33MONOX isoform X4

      UniProtKB/TrEMBL
      A6KAZ6
      Conserved Domains (1) summary
      pfam15302
      Location:1 → 198
      P33MONOX; P33 mono-oxygenase

    4. XM_039095628.2 → XP_038951556.1  putative monooxygenase p33MONOX isoform X1

      UniProtKB/Swiss-Prot
      Q5U2R6, Q7TP81
      UniProtKB/TrEMBL
      A0A8I6GIN5, A6KAZ0
      Conserved Domains (1) summary
      pfam15302
      Location:18 → 304
      P33MONOX; P33 mono-oxygenase

    5. XM_039095636.2 → XP_038951564.1  putative monooxygenase p33MONOX isoform X4

      UniProtKB/TrEMBL
      A6KAZ6
      Conserved Domains (1) summary
      pfam15302
      Location:1 → 198
      P33MONOX; P33 mono-oxygenase
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5U2R6.1 GenPept UniProtKB/Swiss-Prot:Q5U2R6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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