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    Higd2a HIG1 hypoxia inducible domain family, member 2A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 290999, updated on 2-Nov-2024

    Summary

    Official Symbol
    Higd2aprovided by RGD
    Official Full Name
    HIG1 hypoxia inducible domain family, member 2Aprovided by RGD
    Primary source
    RGD:1309691
    See related
    EnsemblRapid:ENSRNOG00000017372 AllianceGenome:RGD:1309691
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309691
    Summary
    Predicted to act upstream of or within mitochondrial respirasome assembly and negative regulation of apoptotic process. Predicted to be located in membrane and mitochondrion. Orthologous to human HIGD2A (HIG1 hypoxia inducible domain family member 2A). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Heart (RPKM 287.6), Kidney (RPKM 266.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Higd2a in Genome Data Viewer
    Location:
    17p14
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (10026961..10027885, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (10021853..10022777, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (10558714..10559638, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene Fas associated factor family member 2 Neighboring gene clathrin, light chain B Neighboring gene NOP16 nucleolar protein Neighboring gene ADP-ribosylation factor like GTPase 10

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    HIG1 domain family member 2A, mitochondrial
    Names
    HIG1 domain family, member 2A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106102.1NP_001099572.1  HIG1 domain family member 2A, mitochondrial

      See identical proteins and their annotated locations for NP_001099572.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474032
      UniProtKB/TrEMBL
      B2GV65, F7FGX2
      Related
      ENSRNOP00000023515.3, ENSRNOT00000023515.8
      Conserved Domains (1) summary
      pfam04588
      Location:4796
      HIG_1_N; Hypoxia induced protein conserved region

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      10026961..10027885 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)