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    OR7E2P olfactory receptor family 7 subfamily E member 2 pseudogene [ Homo sapiens (human) ]

    Gene ID: 8587, updated on 26-Oct-2024

    Summary

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    Official Symbol
    OR7E2Pprovided by HGNC
    Official Full Name
    olfactory receptor family 7 subfamily E member 2 pseudogeneprovided by HGNC
    Primary source
    HGNC:HGNC:8402
    See related
    Ensembl:ENSG00000255203 AllianceGenome:HGNC:8402
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    hg94; OR11-6; OR7F2P; OST245; OR7E51P; OR7E52P; OR7E143P
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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    Genomic context

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    See OR7E2P in Genome Data Viewer
    Location:
    11q14.2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (86856931..86857954, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (86797708..86798731, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (86567973..86568996, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene serine protease 23 Neighboring gene MOB4 pseudogene 2 Neighboring gene olfactory receptor family 7 subfamily E member 13 pseudogene Neighboring gene MPRA-validated peak1379 silencer Neighboring gene PRSS23 antisense RNA 1 Neighboring gene MPRA-validated peak1380 silencer Neighboring gene Sharpr-MPRA regulatory region 12486 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:86651451-86651950 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3828 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3829 Neighboring gene frizzled class receptor 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Organization and evolution of olfactory receptor genes on human chromosome 11. Buettner JA, et al. Genomics, 1998 Oct 1. PMID 9787077
    2. DEFOG: a practical scheme for deciphering families of genes. Fuchs T, et al. Genomics, 2002 Sep. PMID 12213199

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Other Names

    • olfactory receptor, family 7, subfamily E, member 143 pseudogene
    • olfactory receptor, family 7, subfamily E, member 51 pseudogene
    • olfactory receptor, family 7, subfamily E, member 52 pseudogene
    • olfactory receptor, family 7, subfamily F, member 2 pseudogene

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_045004.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000654
      Related
      ENST00000533071.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      86856931..86857954 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      86797708..86798731 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_002166.2: Suppressed sequence

      Description
      NG_002166.2: This RefSeq was permanently suppressed because it is now thought that this gene is a transcribed pseudogene.
    Nucleotide Protein
    Heading Accession and Version

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