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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001283041.3 → NP_001269970.1 ubiquitin carboxyl-terminal hydrolase 25 isoform USP25m
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (USP25m).
- Source sequence(s)
-
AJ010597, AJ010598, BC075792, BM149594, FJ763652
- Consensus CDS
-
CCDS63336.1
- UniProtKB/Swiss-Prot
-
Q9UHP3
- Related
- ENSP00000383044.2, ENST00000400183.7
- Conserved Domains (3) summary
-
- cd02665
Location:170 → 655
- Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- cd14354
Location:15 → 60
- UBA_UBP25; UBA domain found in ubiquitin carboxyl-terminal hydrolase 25 (UBP25) and similar proteins
- pfam00443
Location:168 → 405
- UCH; Ubiquitin carboxyl-terminal hydrolase
-
NM_001283042.3 → NP_001269971.1 ubiquitin carboxyl-terminal hydrolase 25 isoform USP25b
See identical proteins and their annotated locations for NP_001269971.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in an isoform (USP25b) that is shorter than isoform a.
- Source sequence(s)
-
AF170562, AJ010597, AJ010598, BC075792, BM149594
- Consensus CDS
-
CCDS63337.1
- UniProtKB/Swiss-Prot
-
Q9UHP3
- Related
- ENSP00000285681.2, ENST00000285681.6
- Conserved Domains (3) summary
-
- cd02665
Location:170 → 655
- Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- cd14354
Location:15 → 60
- UBA_UBP25; UBA domain found in ubiquitin carboxyl-terminal hydrolase 25 (UBP25) and similar proteins
- pfam00443
Location:168 → 405
- UCH; Ubiquitin carboxyl-terminal hydrolase
-
NM_001352560.2 → NP_001339489.1 ubiquitin carboxyl-terminal hydrolase 25 isoform 4
Status: VALIDATED
- Source sequence(s)
-
AJ010597, AJ010598, BM149594
- Conserved Domains (2) summary
-
- cd02665
Location:37 → 434
- Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- cd20486
Location:547 → 827
- USP25_C; carboxyl-terminal domain of ubiquitin-specific protease 25 (USP25)
-
NM_001352561.2 → NP_001339490.1 ubiquitin carboxyl-terminal hydrolase 25 isoform 5
Status: VALIDATED
- Source sequence(s)
-
AJ010597, AJ010598, BM149594
- UniProtKB/TrEMBL
-
Q9HA22
- Conserved Domains (2) summary
-
- cl02553
Location:163 → 251
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- cd20486
Location:364 → 644
- USP25_C; carboxyl-terminal domain of ubiquitin-specific protease 25 (USP25)
-
NM_001388299.1 → NP_001375228.1 ubiquitin carboxyl-terminal hydrolase 25 isoform 4
Status: VALIDATED
- Source sequence(s)
-
AJ010597, AJ010598
- Conserved Domains (2) summary
-
- cd02665
Location:37 → 434
- Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- cd20486
Location:547 → 827
- USP25_C; carboxyl-terminal domain of ubiquitin-specific protease 25 (USP25)
-
NM_001388300.1 → NP_001375229.1 ubiquitin carboxyl-terminal hydrolase 25 isoform 5
Status: VALIDATED
- Source sequence(s)
-
AJ010597, AJ010598
- UniProtKB/TrEMBL
-
Q9HA22
- Conserved Domains (2) summary
-
- cl02553
Location:163 → 251
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- cd20486
Location:364 → 644
- USP25_C; carboxyl-terminal domain of ubiquitin-specific protease 25 (USP25)
-
NM_001388301.1 → NP_001375230.1 ubiquitin carboxyl-terminal hydrolase 25 isoform 5
Status: VALIDATED
- Source sequence(s)
-
AJ010597, AJ010598
- UniProtKB/TrEMBL
-
Q9HA22
- Conserved Domains (2) summary
-
- cl02553
Location:163 → 251
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- cd20486
Location:364 → 644
- USP25_C; carboxyl-terminal domain of ubiquitin-specific protease 25 (USP25)
-
NM_001388302.1 → NP_001375231.1 ubiquitin carboxyl-terminal hydrolase 25 isoform 6
Status: VALIDATED
- Source sequence(s)
-
AJ010597, AJ010598
- UniProtKB/TrEMBL
-
Q9HA22
- Conserved Domains (2) summary
-
- cl02553
Location:163 → 251
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- cd20486
Location:361 → 641
- USP25_C; carboxyl-terminal domain of ubiquitin-specific protease 25 (USP25)
-
NM_013396.6 → NP_037528.3 ubiquitin carboxyl-terminal hydrolase 25 isoform USP25a
See identical proteins and their annotated locations for NP_037528.3
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) lacks two alternate in-frame exons in the 3' coding region, compared to variant 1, resulting in an isoform (USP25a) that is shorter than isoform a.
- Source sequence(s)
-
AJ010597, AJ010598, BC075792, BM149594
- Consensus CDS
-
CCDS33515.1
- UniProtKB/Swiss-Prot
- C0LSZ0, Q6DHZ9, Q9H9W1, Q9UHP3
- Related
- ENSP00000285679.6, ENST00000285679.10
- Conserved Domains (3) summary
-
- cd02665
Location:170 → 655
- Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- cd14354
Location:15 → 60
- UBA_UBP25; UBA domain found in ubiquitin carboxyl-terminal hydrolase 25 (UBP25) and similar proteins
- cl02553
Location:168 → 298
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000021.9 Reference GRCh38.p14 Primary Assembly
- Range
-
15729982..15880064
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011529529.2 → XP_011527831.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X1
- Conserved Domains (3) summary
-
- cd02665
Location:170 → 655
- Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- cd14354
Location:15 → 60
- UBA_UBP25; UBA domain found in ubiquitin carboxyl-terminal hydrolase 25 (UBP25) and similar proteins
- pfam00443
Location:168 → 405
- UCH; Ubiquitin carboxyl-terminal hydrolase
-
XM_047440749.1 → XP_047296705.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X5
-
XM_047440751.1 → XP_047296707.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X7
-
XM_011529535.3 → XP_011527837.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X8
- Conserved Domains (4) summary
-
- cd02665
Location:170 → 399
- Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- cd14354
Location:15 → 60
- UBA_UBP25; UBA domain found in ubiquitin carboxyl-terminal hydrolase 25 (UBP25) and similar proteins
- cl02553
Location:168 → 298
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- pfam00443
Location:168 → 405
- UCH; Ubiquitin carboxyl-terminal hydrolase
-
XM_047440745.1 → XP_047296701.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X2
-
XM_047440746.1 → XP_047296702.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X3
-
XM_047440748.1 → XP_047296704.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X4
-
XM_047440747.1 → XP_047296703.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X4
-
XM_005260949.5 → XP_005261006.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X6
- Conserved Domains (1) summary
-
- cl02553
Location:163 → 251
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
-
XM_047440750.1 → XP_047296706.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X6
Alternate T2T-CHM13v2.0
Genomic
-
NC_060945.1 Alternate T2T-CHM13v2.0
- Range
-
14085398..14235467
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054324439.1 → XP_054180414.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X1
-
XM_054324444.1 → XP_054180419.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X5
-
XM_054324447.1 → XP_054180422.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X7
-
XM_054324448.1 → XP_054180423.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X8
-
XM_054324438.1 → XP_054180413.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X9
-
XM_054324440.1 → XP_054180415.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X2
-
XM_054324441.1 → XP_054180416.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X3
-
XM_054324443.1 → XP_054180418.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X4
-
XM_054324442.1 → XP_054180417.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X4
-
XM_054324446.1 → XP_054180421.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X6
-
XM_054324445.1 → XP_054180420.1 ubiquitin carboxyl-terminal hydrolase 25 isoform X6