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    OR14A16 olfactory receptor family 14 subfamily A member 16 [ Homo sapiens (human) ]

    Gene ID: 284532, updated on 2-Nov-2024

    Summary

    Official Symbol
    OR14A16provided by HGNC
    Official Full Name
    olfactory receptor family 14 subfamily A member 16provided by HGNC
    Primary source
    HGNC:HGNC:15022
    See related
    Ensembl:ENSG00000196772 AllianceGenome:HGNC:15022
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OR5AT1
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Orthologs
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    Genomic context

    See OR14A16 in Genome Data Viewer
    Location:
    1q44
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (247814660..247824119, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (247245514..247254979, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (247977962..247987421, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 1 subfamily C member 1 Neighboring gene olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) Neighboring gene MPRA-validated peak836 silencer Neighboring gene hydroxysteroid 17-beta dehydrogenase 7 pseudogene 1 Neighboring gene olfactory receptor family 6 subfamily R member 1 pseudogene

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    olfactory receptor 14A16
    Names
    olfactory receptor 5AT1
    olfactory receptor OR1-45
    olfactory receptor, family 5, subfamily AT, member 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_053131.1 RefSeqGene

      Range
      5130..6059
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001001966.2NP_001001966.1  olfactory receptor 14A16

      See identical proteins and their annotated locations for NP_001001966.1

      Status: REVIEWED

      Source sequence(s)
      AC099571
      Consensus CDS
      CCDS31097.1
      UniProtKB/Swiss-Prot
      Q6IF96, Q8NHC5
      UniProtKB/TrEMBL
      A0A126GWP4
      Related
      ENSP00000493024.1, ENST00000641093.1
      Conserved Domains (2) summary
      pfam00001
      Location:39287
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:29295
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      247814660..247824119 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      247245514..247254979 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)