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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_032868.1 RefSeqGene
- Range
-
5119..48423
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001160223.2 → NP_001153695.1 E3 ubiquitin-protein ligase RNF170 isoform a
See identical proteins and their annotated locations for NP_001153695.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 2 encode the same isoform (a).
- Source sequence(s)
-
AA973979, AC087533, BC039461, BG910500
- Consensus CDS
-
CCDS6138.1
- UniProtKB/Swiss-Prot
- D3DSY6, E9PIL4, Q7Z483, Q86YC0, Q8IXR7, Q8N2B5, Q8N5G9, Q8NG30, Q96K19, Q9H0V6
- Related
- ENSP00000445725.1, ENST00000534961.5
- Conserved Domains (2) summary
-
- cd00162
Location:87 → 133
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
- pfam06803
Location:203 → 239
- DUF1232; Protein of unknown function (DUF1232)
-
NM_001160224.2 → NP_001153696.1 E3 ubiquitin-protein ligase RNF170 isoform b
See identical proteins and their annotated locations for NP_001153696.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' and 3' UTRs and has multiple coding region differences compared to variant 1. This results in a shorter isoform (b) with a distinct C-terminus, compared to isoform a.
- Source sequence(s)
-
AC087533, BC032393, DA751961
- Consensus CDS
-
CCDS55230.1
- UniProtKB/Swiss-Prot
-
Q96K19
- Related
- ENSP00000326138.3, ENST00000319104.7
- Conserved Domains (1) summary
-
- cd00162
Location:87 → 132
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
-
NM_001160225.2 → NP_001153697.1 E3 ubiquitin-protein ligase RNF170 isoform c
See identical proteins and their annotated locations for NP_001153697.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The resulting isoform (c) has a shorter N-terminus compared to isoform a.
- Source sequence(s)
-
AA973979, AC087533, BC058289
- Consensus CDS
-
CCDS55229.1
- UniProtKB/Swiss-Prot
-
Q96K19
- Related
- ENSP00000435782.1, ENST00000526349.5
- Conserved Domains (2) summary
-
- pfam06803
Location:119 → 153
- DUF1232; Protein of unknown function (DUF1232)
- cd16553
Location:3 → 46
- RING-HC_RNF170; RING finger, HC subclass, found in RING finger protein 170 (RNF170) and similar proteins
-
NM_030954.4 → NP_112216.3 E3 ubiquitin-protein ligase RNF170 isoform a
See identical proteins and their annotated locations for NP_112216.3
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (a).
- Source sequence(s)
-
AA973979, AC087533, AK225568
- Consensus CDS
-
CCDS6138.1
- UniProtKB/Swiss-Prot
- D3DSY6, E9PIL4, Q7Z483, Q86YC0, Q8IXR7, Q8N2B5, Q8N5G9, Q8NG30, Q96K19, Q9H0V6
- Related
- ENSP00000434797.1, ENST00000527424.6
- Conserved Domains (2) summary
-
- cd00162
Location:87 → 133
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
- pfam06803
Location:203 → 239
- DUF1232; Protein of unknown function (DUF1232)
RNA
-
NR_027668.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AA973979, AC087533, AK090864
-
NR_027669.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) uses an alternate 5' exon and lacks an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AA973979, AC087533, BC013422, DA751961
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000008.11 Reference GRCh38.p14 Primary Assembly
- Range
-
42849637..42897299 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047422281.1 → XP_047278237.1 E3 ubiquitin-protein ligase RNF170 isoform X4
-
XM_011544666.4 → XP_011542968.1 E3 ubiquitin-protein ligase RNF170 isoform X2
See identical proteins and their annotated locations for XP_011542968.1
- UniProtKB/Swiss-Prot
- D3DSY6, E9PIL4, Q7Z483, Q86YC0, Q8IXR7, Q8N2B5, Q8N5G9, Q8NG30, Q96K19, Q9H0V6
- Conserved Domains (2) summary
-
- cd00162
Location:87 → 133
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
- pfam06803
Location:203 → 239
- DUF1232; Protein of unknown function (DUF1232)
-
XM_047422279.1 → XP_047278235.1 E3 ubiquitin-protein ligase RNF170 isoform X2
- UniProtKB/Swiss-Prot
- D3DSY6, E9PIL4, Q7Z483, Q86YC0, Q8IXR7, Q8N2B5, Q8N5G9, Q8NG30, Q96K19, Q9H0V6
-
XM_006716405.4 → XP_006716468.1 E3 ubiquitin-protein ligase RNF170 isoform X4
- Conserved Domains (1) summary
-
- pfam06803
Location:153 → 189
- DUF1232; Protein of unknown function (DUF1232)
-
XM_006716404.3 → XP_006716467.1 E3 ubiquitin-protein ligase RNF170 isoform X2
See identical proteins and their annotated locations for XP_006716467.1
- UniProtKB/Swiss-Prot
- D3DSY6, E9PIL4, Q7Z483, Q86YC0, Q8IXR7, Q8N2B5, Q8N5G9, Q8NG30, Q96K19, Q9H0V6
- Conserved Domains (2) summary
-
- cd00162
Location:87 → 133
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
- pfam06803
Location:203 → 239
- DUF1232; Protein of unknown function (DUF1232)
-
XM_017013881.2 → XP_016869370.1 E3 ubiquitin-protein ligase RNF170 isoform X2
- UniProtKB/Swiss-Prot
- D3DSY6, E9PIL4, Q7Z483, Q86YC0, Q8IXR7, Q8N2B5, Q8N5G9, Q8NG30, Q96K19, Q9H0V6
- Conserved Domains (2) summary
-
- cd00162
Location:87 → 133
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
- pfam06803
Location:203 → 239
- DUF1232; Protein of unknown function (DUF1232)
-
XM_047422280.1 → XP_047278236.1 E3 ubiquitin-protein ligase RNF170 isoform X3
-
XM_047422278.1 → XP_047278234.1 E3 ubiquitin-protein ligase RNF170 isoform X1
-
XM_047422282.1 → XP_047278238.1 E3 ubiquitin-protein ligase RNF170 isoform X5
-
XM_047422285.1 → XP_047278241.1 E3 ubiquitin-protein ligase RNF170 isoform X8
- Related
- ENSP00000325969.5, ENST00000319073.5
-
XM_047422288.1 → XP_047278244.1 E3 ubiquitin-protein ligase RNF170 isoform X11
-
XM_047422287.1 → XP_047278243.1 E3 ubiquitin-protein ligase RNF170 isoform X10
-
XM_047422284.1 → XP_047278240.1 E3 ubiquitin-protein ligase RNF170 isoform X7
- Related
- ENSP00000436416.1, ENST00000531440.5
-
XM_047422283.1 → XP_047278239.1 E3 ubiquitin-protein ligase RNF170 isoform X6
-
XM_047422286.1 → XP_047278242.1 E3 ubiquitin-protein ligase RNF170 isoform X9
Alternate T2T-CHM13v2.0
Genomic
-
NC_060932.1 Alternate T2T-CHM13v2.0
- Range
-
43117750..43166240 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054361308.1 → XP_054217283.1 E3 ubiquitin-protein ligase RNF170 isoform X2
- UniProtKB/Swiss-Prot
- D3DSY6, E9PIL4, Q7Z483, Q86YC0, Q8IXR7, Q8N2B5, Q8N5G9, Q8NG30, Q96K19, Q9H0V6
-
XM_054361312.1 → XP_054217287.1 E3 ubiquitin-protein ligase RNF170 isoform X4
-
XM_054361311.1 → XP_054217286.1 E3 ubiquitin-protein ligase RNF170 isoform X4
-
XM_054361307.1 → XP_054217282.1 E3 ubiquitin-protein ligase RNF170 isoform X2
- UniProtKB/Swiss-Prot
- D3DSY6, E9PIL4, Q7Z483, Q86YC0, Q8IXR7, Q8N2B5, Q8N5G9, Q8NG30, Q96K19, Q9H0V6
-
XM_054361309.1 → XP_054217284.1 E3 ubiquitin-protein ligase RNF170 isoform X2
- UniProtKB/Swiss-Prot
- D3DSY6, E9PIL4, Q7Z483, Q86YC0, Q8IXR7, Q8N2B5, Q8N5G9, Q8NG30, Q96K19, Q9H0V6
-
XM_054361310.1 → XP_054217285.1 E3 ubiquitin-protein ligase RNF170 isoform X3
-
XM_054361306.1 → XP_054217281.1 E3 ubiquitin-protein ligase RNF170 isoform X1
-
XM_054361313.1 → XP_054217288.1 E3 ubiquitin-protein ligase RNF170 isoform X5
-
XM_054361316.1 → XP_054217291.1 E3 ubiquitin-protein ligase RNF170 isoform X8
-
XM_054361319.1 → XP_054217294.1 E3 ubiquitin-protein ligase RNF170 isoform X11
-
XM_054361318.1 → XP_054217293.1 E3 ubiquitin-protein ligase RNF170 isoform X10
-
XM_054361315.1 → XP_054217290.1 E3 ubiquitin-protein ligase RNF170 isoform X7
-
XM_054361314.1 → XP_054217289.1 E3 ubiquitin-protein ligase RNF170 isoform X6
-
XM_054361317.1 → XP_054217292.1 E3 ubiquitin-protein ligase RNF170 isoform X9