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    TRI1 Tri1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855273, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TRI1
    Official Full Name
    Tri1p
    Primary source
    SGD:S000004846
    Locus tag
    YMR233W
    See related
    AllianceGenome:SGD:S000004846; FungiDB:YMR233W; VEuPathDB:YMR233W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable RNA polymerase I cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in nucleolar large rRNA transcription by RNA polymerase I and transcription initiation from RNA polymerase I promoter. Located in cytoplasm and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See TRI1 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (739185..739865)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene tethering complex subunit PEP5 Neighboring gene Fus2p Neighboring gene RNA-DNA hybrid ribonuclease Neighboring gene GTPase-activating protein RNA1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomewide Elucidation of Drug Resistance Mechanisms for Systemically Used Antifungal Drugs Amphotericin B, Caspofungin, and Voriconazole in the Budding Yeast. Balkan C, et al. Antimicrob Agents Chemother, 2019 Sep. PMID 31209012, Free PMC Article
    2. Transcription of chromosomal rRNA genes by both RNA polymerase I and II in yeast uaf30 mutants lacking the 30 kDa subunit of transcription factor UAF. Siddiqi IN, et al. EMBO J, 2001 Aug 15. PMID 11500378, Free PMC Article
    3. Topoisomerase I-dependent viability loss in saccharomyces cerevisiae mutants defective in both SUMO conjugation and DNA repair. Chen XL, et al. Genetics, 2007 Sep. PMID 17603101, Free PMC Article
    4. Efficient PCR-based gene disruption in Saccharomyces strains using intergenic primers. Reid RJ, et al. Yeast, 2002 Mar 15. PMID 11870855
    5. Bayesian Markov Random Field analysis for protein function prediction based on network data. Kourmpetis YA, et al. PLoS One, 2010 Feb 24. PMID 20195360, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA polymerase I cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in nucleolar large rRNA transcription by RNA polymerase I IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at RNA polymerase I promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of RNA polymerase I upstream activating factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus HDA PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Tri1p
    NP_013960.1
    • Non-essential sumoylated hypothetical protein; similar to components of human SWI/SNF complex including SMRD3; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, nucleus and nucleolus; TRI1 has a paralog, UAF30, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      739185..739865
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182740.1 → NP_013960.1  TPA: Tri1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013960.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W059, Q05024
      UniProtKB/TrEMBL
      A6ZMU6, B3LMC2, B5VQ01, C7GRB7, C8ZF98, G2WKU1, N1NYN9
      Conserved Domains (1) summary
      COG5531
      Location:1 → 226
      Rsc6; Chromatin remodeling complex protein RSC6, contains SWIB domain [Chromatin structure and dynamics]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q05024.1

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