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    RKM4 ribosomal lysine N-methyltransferase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851844, updated on 1-Aug-2024

    Summary

    Gene symbol
    RKM4
    Gene description
    ribosomal lysine N-methyltransferase
    Primary source
    FungiDB:YDR257C
    Locus tag
    YDR257C
    See related
    SGD:S000002665; AllianceGenome:SGD:S000002665; VEuPathDB:YDR257C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RMS1; SET7
    Summary
    Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine monomethylation. Located in nucleus. Orthologous to human SETD6 (SET domain containing 6, protein lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See RKM4 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (969990..971474, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene ubiquitin-protein ligase RMD5 Neighboring gene catalase A Neighboring gene chaperone ATPase HSP78 Neighboring gene Yap6p

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-lysine N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein-lysine N-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-lysine N-methyltransferase activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    enables protein-lysine N-methyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in peptidyl-lysine monomethylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in peptidyl-lysine monomethylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in peptidyl-lysine monomethylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ribosomal lysine N-methyltransferase
    NP_010543.1
    • Ribosomal lysine methyltransferase; specific for monomethylation of Rpl42ap and Rpl42bp (lysine 55); nuclear SET-domain containing protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      969990..971474 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180565.1NP_010543.1  TPA: ribosomal lysine N-methyltransferase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010543.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VSN7, Q07015, Q12504
      UniProtKB/TrEMBL
      B3LG33, C7GTJ2, C8Z5G9, N1P6Q0
      Conserved Domains (1) summary
      cd19178
      Location:21281
      SET_SETD6; SET domain found in SET domain-containing protein 6 (SETD6) and similar proteins