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    FIG2 Fig2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850451, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FIG2
    Official Full Name
    Fig2p
    Primary source
    SGD:S000000685
    Locus tag
    YCR089W
    See related
    AllianceGenome:SGD:S000000685; FungiDB:YCR089W; VEuPathDB:YCR089W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in cell morphogenesis involved in conjugation with cellular fusion; cytogamy; and invasive growth in response to glucose limitation. Located in fungal-type cell wall and mating projection. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See FIG2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_001135.5 (267434..272263)

    Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Abp1p Neighboring gene uncharacterized protein Neighboring gene putative serine/threonine protein kinase KIN82

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001135.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of Fig2p in agglutination in Saccharomyces cerevisiae. Jue CK, et al. Eukaryot Cell, 2002 Oct. PMID 12455701, Free PMC Article
    2. Maintenance of mating cell integrity requires the adhesin Fig2p. Zhang M, et al. Eukaryot Cell, 2002 Oct. PMID 12455698, Free PMC Article
    3. Pervasive and dynamic transcription initiation in Saccharomyces cerevisiae. Lu Z, et al. Genome Res, 2019 Jul. PMID 31076411, Free PMC Article
    4. Accelerated and adaptive evolution of yeast sexual adhesins. Xie X, et al. Mol Biol Evol, 2011 Nov. PMID 21633112, Free PMC Article
    5. Conserved WCPL and CX4C domains mediate several mating adhesin interactions in Saccharomyces cerevisiae. Huang G, et al. Genetics, 2009 May. PMID 19299340, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell morphogenesis involved in conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cytogamy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in filamentous growth of a population of unicellular organisms IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in invasive growth in response to glucose limitation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to pheromone IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mating projection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Fig2p
    NP_010013.2
    • Cell wall adhesin, expressed specifically during mating; may be involved in maintenance of cell wall integrity during mating; FIG2 has a paralog, AGA1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001135.5 Reference assembly

      Range
      267434..272263
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178795.1 → NP_010013.2  TPA: Fig2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010013.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VR89, P25653
      UniProtKB/TrEMBL
      A6ZTR0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25653.2

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