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    Snrnp48 small nuclear ribonucleoprotein U11/U12 subunit 48 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291060, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Snrnp48provided by RGD
    Official Full Name
    small nuclear ribonucleoprotein U11/U12 subunit 48provided by RGD
    Primary source
    RGD:1309020
    See related
    EnsemblRapid:ENSRNOG00000013756 AllianceGenome:RGD:1309020
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309020
    Summary
    Predicted to enable metal ion binding activity. Predicted to be part of U12-type spliceosomal complex. Predicted to be active in cytosol and nucleoplasm. Orthologous to human SNRNP48 (small nuclear ribonucleoprotein U11/U12 subunit 48). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 107.2), Lung (RPKM 93.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Snrnp48 in Genome Data Viewer
    Location:
    17p12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (26801818..26821605, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (26596266..26616058, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (27243732..27279271, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene thioredoxin domain containing 5 Neighboring gene bone morphogenetic protein 6 Neighboring gene U6 spliceosomal RNA Neighboring gene desmoplakin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. Will CL, et al. RNA, 2004 Jun. PMID 15146077, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of U12-type spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U12-type spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    U11/U12 small nuclear ribonucleoprotein 48 kDa protein
    Names
    small nuclear ribonucleoprotein 48 (U11/U12)
    small nuclear ribonucleoprotein 48k (U11/U12)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106107.1 → NP_001099577.1  U11/U12 small nuclear ribonucleoprotein 48 kDa protein

      See identical proteins and their annotated locations for NP_001099577.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473977
      UniProtKB/TrEMBL
      A6J7A8
      Conserved Domains (1) summary
      pfam05253
      Location:57 → 79
      zf-U11-48K; U11-48K-like CHHC zinc finger

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      26801818..26821605 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006253788.5 → XP_006253850.1  U11/U12 small nuclear ribonucleoprotein 48 kDa protein isoform X3

      Related
      ENSRNOP00000110712.1, ENSRNOT00000145911.1
      Conserved Domains (1) summary
      pfam05253
      Location:57 → 79
      zf-U11-48K; U11-48K-like CHHC zinc finger

    2. XM_039095479.2 → XP_038951407.1  U11/U12 small nuclear ribonucleoprotein 48 kDa protein isoform X2

      UniProtKB/TrEMBL
      A6J7A9, D3ZJA5
      Related
      ENSRNOP00000018508.6, ENSRNOT00000018508.8
      Conserved Domains (1) summary
      pfam05253
      Location:57 → 79
      zf-U11-48K; U11-48K-like CHHC zinc finger

    3. XM_006253787.5 → XP_006253849.1  U11/U12 small nuclear ribonucleoprotein 48 kDa protein isoform X1

      UniProtKB/TrEMBL
      A0A8I6A3E2
      Related
      ENSRNOP00000085198.1, ENSRNOT00000110730.2
      Conserved Domains (1) summary
      pfam05253
      Location:57 → 79
      zf-U11-48K; U11-48K-like CHHC zinc finger

    4. XM_063276160.1 → XP_063132230.1  U11/U12 small nuclear ribonucleoprotein 48 kDa protein isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version

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