U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    KIAA0825 KIAA0825 [ Homo sapiens (human) ]

    Gene ID: 285600, updated on 10-Oct-2024

    Summary

    Official Symbol
    KIAA0825provided by HGNC
    Official Full Name
    KIAA0825provided by HGNC
    Primary source
    HGNC:HGNC:28532
    See related
    Ensembl:ENSG00000185261 MIM:617266; AllianceGenome:HGNC:28532
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PAPA10; C5orf36
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See KIAA0825 in Genome Data Viewer
    Location:
    5q15
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (94150851..94618604, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (94634907..95102987, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (93486556..93954309, complement)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:93091910-93092657 Neighboring gene ARB2 cotranscriptional regulator A Neighboring gene nucleophosmin 1 pseudogene 27 Neighboring gene POU domain class 5, transcription factor 2 Neighboring gene VISTA enhancer hs271 Neighboring gene MPRA-validated peak5355 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:93361212-93361712 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22789 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr5:93393287-93393833 Neighboring gene uncharacterized LOC105379087 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr5:93520520-93521028 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:93690795-93691426 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:93692061-93692692 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:93697863-93698503 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr5:93800512-93801711 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:93908890-93909675 Neighboring gene FAST kinase domains 1 pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:93953323-93954187 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22791 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22792 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:93968657-93969156 Neighboring gene MT-ND5 pseudogene 12 Neighboring gene MT-CYB pseudogene 35 Neighboring gene MT-ND6 pseudogene 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22793 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr5:94128945-94130144 Neighboring gene SMC5-SMC6 complex localization factor 1 Neighboring gene multiple C2 and transmembrane domain containing 1 Neighboring gene ribosomal protein L7 pseudogene 18 Neighboring gene MCTP1 antisense RNA 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    Polydactyly, postaxial, type a10
    MedGen: C5193129 OMIM: 618498 GeneReviews: Not available
    Compare labs

    EBI GWAS Catalog

    Description
    A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.
    EBI GWAS Catalog
    Genome-wide association study identifies ALLC polymorphisms correlated with FEV₁ change by corticosteroid.
    EBI GWAS Catalog
    Genome-wide association study of diabetic retinopathy in a Taiwanese population.
    EBI GWAS Catalog

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ27431, KIAA0825, MGC34713, DKFZp686F0372

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    uncharacterized protein KIAA0825

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145678.3NP_001139150.1  uncharacterized protein KIAA0825 isoform 1

      See identical proteins and their annotated locations for NP_001139150.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC025766, AC093311, AC104127, AC117521
      Consensus CDS
      CCDS93745.1
      UniProtKB/Swiss-Prot
      A0A088AWM3, O94914, Q6ZNN2, Q8IV33
      UniProtKB/TrEMBL
      A0A804HHT9
      Related
      ENSP00000506760.1, ENST00000682413.1
      Conserved Domains (1) summary
      pfam14906
      Location:515832
      DUF4495; Domain of unknown function (DUF4495)
    2. NM_001385712.1NP_001372641.1  uncharacterized protein KIAA0825 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311, AC104127, AC117521
      Consensus CDS
      CCDS93746.1
      UniProtKB/Swiss-Prot
      A0A088AWM3, O94914, Q6ZNN2, Q8IV33
      UniProtKB/TrEMBL
      A0A994J718
      Conserved Domains (1) summary
      pfam14906
      Location:515832
      DUF4495; Domain of unknown function (DUF4495)
    3. NM_001385713.1NP_001372642.1  uncharacterized protein KIAA0825 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311, AC117521
      UniProtKB/Swiss-Prot
      A0A088AWM3, O94914, Q6ZNN2, Q8IV33
      Conserved Domains (1) summary
      pfam14906
      Location:515832
      DUF4495; Domain of unknown function (DUF4495)
    4. NM_001385714.1NP_001372643.1  uncharacterized protein KIAA0825 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
    5. NM_001385715.1NP_001372644.1  uncharacterized protein KIAA0825 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
      Consensus CDS
      CCDS4070.1
    6. NM_001385716.1NP_001372645.1  uncharacterized protein KIAA0825 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
      Consensus CDS
      CCDS4070.1
    7. NM_001385717.1NP_001372646.1  uncharacterized protein KIAA0825 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
      Consensus CDS
      CCDS4070.1
    8. NM_001385719.1NP_001372648.1  uncharacterized protein KIAA0825 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
      Consensus CDS
      CCDS4070.1
    9. NM_001385720.1NP_001372649.1  uncharacterized protein KIAA0825 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
      Consensus CDS
      CCDS4070.1
    10. NM_001385721.1NP_001372650.1  uncharacterized protein KIAA0825 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
      Consensus CDS
      CCDS4070.1
    11. NM_001385722.1NP_001372651.1  uncharacterized protein KIAA0825 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
      Consensus CDS
      CCDS4070.1
    12. NM_001385723.1NP_001372652.1  uncharacterized protein KIAA0825 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
      Consensus CDS
      CCDS4070.1
    13. NM_001385724.1NP_001372653.1  uncharacterized protein KIAA0825 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
    14. NM_001385728.1NP_001372657.1  uncharacterized protein KIAA0825 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
      Consensus CDS
      CCDS4070.1
    15. NM_001385729.1NP_001372658.1  uncharacterized protein KIAA0825 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
      Consensus CDS
      CCDS4070.1
    16. NM_001385730.1NP_001372659.1  uncharacterized protein KIAA0825 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
      Consensus CDS
      CCDS4070.1
    17. NM_001388325.1NP_001375254.1  uncharacterized protein KIAA0825 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311, AC104127, AC117521
      Consensus CDS
      CCDS93746.1
      UniProtKB/Swiss-Prot
      A0A088AWM3, O94914, Q6ZNN2, Q8IV33
      UniProtKB/TrEMBL
      A0A994J718
      Related
      ENSP00000515512.1, ENST00000703867.1
      Conserved Domains (1) summary
      pfam14906
      Location:515832
      DUF4495; Domain of unknown function (DUF4495)
    18. NM_173665.3NP_775936.1  uncharacterized protein KIAA0825 isoform 2

      See identical proteins and their annotated locations for NP_775936.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an early polyA signal that omits 16 exons from the 3' end, compared to variant 1. The resulting isoform (2) has a substantially shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AK308195, BC035515, BX648338
      Consensus CDS
      CCDS4070.1
      UniProtKB/Swiss-Prot
      Q8IV33
      Related
      ENSP00000331385.6, ENST00000329378.7

    RNA

    1. NR_169751.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC010448, AC025766, AC093311, AC117521
    2. NR_169752.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
    3. NR_169753.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311
    4. NR_169754.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC025766, AC093311

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      94150851..94618604 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047417110.1XP_047273066.1  uncharacterized protein KIAA0825 isoform X3

    2. XM_011543329.3XP_011541631.1  uncharacterized protein KIAA0825 isoform X1

      See identical proteins and their annotated locations for XP_011541631.1

      UniProtKB/Swiss-Prot
      A0A088AWM3, O94914, Q6ZNN2, Q8IV33
      Conserved Domains (1) summary
      pfam14906
      Location:515832
      DUF4495; Domain of unknown function (DUF4495)
    3. XM_017009374.2XP_016864863.1  uncharacterized protein KIAA0825 isoform X5

      UniProtKB/Swiss-Prot
      A0A088AWM3, O94914, Q6ZNN2, Q8IV33
    4. XM_011543330.3XP_011541632.1  uncharacterized protein KIAA0825 isoform X2

      UniProtKB/Swiss-Prot
      A0A088AWM3, O94914, Q6ZNN2, Q8IV33
      Conserved Domains (1) summary
      pfam14906
      Location:515832
      DUF4495; Domain of unknown function (DUF4495)
    5. XM_011543324.3XP_011541626.1  uncharacterized protein KIAA0825 isoform X1

      See identical proteins and their annotated locations for XP_011541626.1

      UniProtKB/Swiss-Prot
      A0A088AWM3, O94914, Q6ZNN2, Q8IV33
      Conserved Domains (1) summary
      pfam14906
      Location:515832
      DUF4495; Domain of unknown function (DUF4495)
    6. XM_011543328.4XP_011541630.1  uncharacterized protein KIAA0825 isoform X1

      See identical proteins and their annotated locations for XP_011541630.1

      UniProtKB/Swiss-Prot
      A0A088AWM3, O94914, Q6ZNN2, Q8IV33
      Conserved Domains (1) summary
      pfam14906
      Location:515832
      DUF4495; Domain of unknown function (DUF4495)
    7. XM_011543325.4XP_011541627.1  uncharacterized protein KIAA0825 isoform X1

      See identical proteins and their annotated locations for XP_011541627.1

      UniProtKB/Swiss-Prot
      A0A088AWM3, O94914, Q6ZNN2, Q8IV33
      Conserved Domains (1) summary
      pfam14906
      Location:515832
      DUF4495; Domain of unknown function (DUF4495)
    8. XM_011543327.3XP_011541629.1  uncharacterized protein KIAA0825 isoform X1

      See identical proteins and their annotated locations for XP_011541629.1

      UniProtKB/Swiss-Prot
      A0A088AWM3, O94914, Q6ZNN2, Q8IV33
      Conserved Domains (1) summary
      pfam14906
      Location:515832
      DUF4495; Domain of unknown function (DUF4495)
    9. XM_011543335.3XP_011541637.1  uncharacterized protein KIAA0825 isoform X6

      UniProtKB/Swiss-Prot
      A0A088AWM3, O94914, Q6ZNN2, Q8IV33
      Conserved Domains (1) summary
      pfam14906
      Location:403720
      DUF4495; Domain of unknown function (DUF4495)
    10. XM_047417111.1XP_047273067.1  uncharacterized protein KIAA0825 isoform X7

    11. XM_017009373.2XP_016864862.1  uncharacterized protein KIAA0825 isoform X4

      UniProtKB/Swiss-Prot
      A0A088AWM3, O94914, Q6ZNN2, Q8IV33
    12. XM_047417112.1XP_047273068.1  uncharacterized protein KIAA0825 isoform X8

    RNA

    1. XR_948246.3 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      94634907..95102987 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054352426.1XP_054208401.1  uncharacterized protein KIAA0825 isoform X3

    2. XM_054352421.1XP_054208396.1  uncharacterized protein KIAA0825 isoform X1

    3. XM_054352428.1XP_054208403.1  uncharacterized protein KIAA0825 isoform X5

    4. XM_054352425.1XP_054208400.1  uncharacterized protein KIAA0825 isoform X2

    5. XM_054352420.1XP_054208395.1  uncharacterized protein KIAA0825 isoform X1

    6. XM_054352422.1XP_054208397.1  uncharacterized protein KIAA0825 isoform X1

    7. XM_054352423.1XP_054208398.1  uncharacterized protein KIAA0825 isoform X1

    8. XM_054352424.1XP_054208399.1  uncharacterized protein KIAA0825 isoform X1

    9. XM_054352429.1XP_054208404.1  uncharacterized protein KIAA0825 isoform X6

    10. XM_054352430.1XP_054208405.1  uncharacterized protein KIAA0825 isoform X7

    11. XM_054352427.1XP_054208402.1  uncharacterized protein KIAA0825 isoform X4

    12. XM_054352431.1XP_054208406.1  uncharacterized protein KIAA0825 isoform X8

    RNA

    1. XR_008487111.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001385718.1: Suppressed sequence

      Description
      NM_001385718.1: This RefSeq was removed because currently there is support for the transcript but not for the protein.