U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    pqn-59 Prion-like (glutamine/asparagine-rich) domain bearing protein pqn-59 [ Caenorhabditis elegans ]

    Gene ID: 266819, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    pqn-59
    Official Full Name
    Prion-like (glutamine/asparagine-rich) domain bearing protein pqn-59
    Primary source
    WormBase:WBGene00004143
    Locus tag
    CELE_R119.4
    See related
    AllianceGenome:WB:WBGene00004143
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in cytoplasm and nucleus. Is expressed widely. Orthologous to several human genes including UBAP2L (ubiquitin associated protein 2 like). [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See pqn-59 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (379071..381902, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene RRM domain-containing protein Neighboring gene Aminopeptidase P N-terminal domain-containing protein Neighboring gene DeHydrogenases, Short chain Neighboring gene Transcription initiation factor TFIID subunit 4 Neighboring gene Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 Neighboring gene ubiquitinyl hydrolase 1 Neighboring gene WD_REPEATS_REGION domain-containing protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. PQN-59 antagonizes microRNA-mediated repression during post-embryonic temporal patterning and modulates translation and stress granule formation in C. elegans. Carlston C, et al. PLoS Genet, 2021 Nov. PMID 34807903, Free PMC Article
    2. PQN-59 and GTBP-1 contribute to stress granule formation but are not essential for their assembly in C. elegans embryos. Abbatemarco S, et al. J Cell Sci, 2021 Nov 15. PMID 34661238, Free PMC Article
    3. Pairing centers recruit a Polo-like kinase to orchestrate meiotic chromosome dynamics in C. elegans. Harper NC, et al. Dev Cell, 2011 Nov 15. PMID 22018922, Free PMC Article
    4. Translational control of the oogenic program by components of OMA ribonucleoprotein particles in Caenorhabditis elegans. Spike CA, et al. Genetics, 2014 Dec. PMID 25261697, Free PMC Article
    5. LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans. Tsukamoto T, et al. Genetics, 2017 Aug. PMID 28576864, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PQN-59 antagonizes microRNA-mediated repression during post-embryonic temporal patterning and modulates translation and stress granule formation in C. elegans.
      Title: PQN-59 antagonizes microRNA-mediated repression during post-embryonic temporal patterning and modulates translation and stress granule formation in C. elegans.
    2. PQN-59 and GTBP-1 contribute to stress granule formation but are not essential for their assembly in C. elegans embryos.
      Title: PQN-59 and GTBP-1 contribute to stress granule formation but are not essential for their assembly in C. elegans embryos.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Prion-like (glutamine/asparagine-rich) domain bearing protein pqn-59
    NP_490727.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      379071..381902 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058326.8 → NP_490727.1  Prion-like (glutamine/asparagine-rich) domain bearing protein pqn-59 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490727.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O61708
      Conserved Domains (1) summary
      cd14277
      Location:31 → 68
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools