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    ERP5 Erp5p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856510, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ERP5
    Official Full Name
    Erp5p
    Primary source
    SGD:S000001152
    Locus tag
    YHR110W
    See related
    AllianceGenome:SGD:S000001152; FungiDB:YHR110W; VEuPathDB:YHR110W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Located in endoplasmic reticulum. Orthologous to human TMED4 (transmembrane p24 trafficking protein 4) and TMED9 (transmembrane p24 trafficking protein 9). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See ERP5 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (332282..332920)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol 4-phosphate-binding protein Neighboring gene cytochrome c lysine N-methyltransferase Neighboring gene Uba4p Neighboring gene putative cystathionine beta-lyase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Erp1p and Erp2p, partners for Emp24p and Erv25p in a yeast p24 complex. Marzioch M, et al. Mol Biol Cell, 1999 Jun. PMID 10359606, Free PMC Article
    2. The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae. Springer S, et al. Proc Natl Acad Sci U S A, 2000 Apr 11. PMID 10737764, Free PMC Article
    3. Isoform-selective oligomer formation of Saccharomyces cerevisiae p24 family proteins. Hirata R, et al. J Biol Chem, 2013 Dec 27. PMID 24217251, Free PMC Article
    4. A computationally guided protein-interaction screen uncovers coiled-coil interactions involved in vesicular trafficking. Zhang H, et al. J Mol Biol, 2009 Sep 11. PMID 19591838
    5. Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII. Johnston M, et al. Science, 1994 Sep 30. PMID 8091229

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Erp5p
    NP_011978.1
    • Protein with similarity to Emp24p and Erv25p; member of the p24 family involved in ER to Golgi transport

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      332282..332920
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179240.1 → NP_011978.1  TPA: Erp5p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011978.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DL60, P38819
      UniProtKB/TrEMBL
      A6ZT18, B3LSM5, C7GLZ6, C8Z9Q3, G2WFI4, N1P2R9
      Conserved Domains (1) summary
      pfam01105
      Location:21 → 206
      EMP24_GP25L; emp24/gp25L/p24 family/GOLD
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38819.1

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