ARA2 D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2 [Saccharomyces cerevisiae S288C] - Gene

Summary

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Official Symbol: ARA2
Official Full Name: D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2
Primary source: SGD:S000004644
Locus tag: YMR041C
See related: AllianceGenome:SGD:S000004644; FungiDB:YMR041C; VEuPathDB:YMR041C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables D-arabinose 1-dehydrogenase [NAD(P)+] activity. Involved in dehydro-D-arabinono-1,4-lactone biosynthetic process. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See ARA2 in Genome Data Viewer

Location:: chromosome: XIII

Exon count:: 1

Sequence:: Chromosome: XIII; NC_001145.3 (350966..351973, complement)

Chromosome XIII - NC_001145.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

It demonstrates that Ara2p, not Ara1p, mainly contributes to the production of Erythroascorbic acid from d-arabinose in S. cerevisiae.
Title: NAD+-specific D-arabinose dehydrogenase and its contribution to erythroascorbic acid production in Saccharomyces cerevisiae.

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables D-arabinose 1-dehydrogenase (NAD+) activity	IEA Inferred from Electronic Annotation more info
enables D-arabinose 1-dehydrogenase [NAD(P)+] activity	IBA Inferred from Biological aspect of Ancestor more info
enables D-arabinose 1-dehydrogenase [NAD(P)+] activity	IDA Inferred from Direct Assay more info	PubMed
enables D-arabinose 1-dehydrogenase [NAD(P)+] activity	IEA Inferred from Electronic Annotation more info
enables D-arabinose 1-dehydrogenase [NAD(P)+] activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in dehydro-D-arabinono-1,4-lactone biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in dehydro-D-arabinono-1,4-lactone biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2

NP_013755.1

EC 1.1.1.116

NAD-dependent arabinose dehydrogenase; involved in biosynthesis of dehydro-D-arabinono-1,4-lactone; similar to plant L-galactose dehydrogenase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001145.3 Reference assembly

Range

350966..351973 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001182538.1 → NP_013755.1 TPA: D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2 [Saccharomyces cerevisiae S288C]

Status: REVIEWED

UniProtKB/Swiss-Prot

D6VZL6, Q04212, Q1XGQ6

UniProtKB/TrEMBL

A6ZMA3, B3LLU0, B5VPH1, C7GL78, C8ZEP8, G2WK94, N1NY81

Conserved Domains (1) summary

cd19164
Location:2 → 301

AKR_ARA2; D-arabinose 1-dehydrogenase (ARA2) and similar proteins