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    Snrnp25 small nuclear ribonucleoprotein U11/U12 subunit 25 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287170, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Snrnp25provided by RGD
    Official Full Name
    small nuclear ribonucleoprotein U11/U12 subunit 25provided by RGD
    Primary source
    RGD:1310922
    See related
    AllianceGenome:RGD:1310922
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310922
    Summary
    Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytosol; intercellular bridge; and nucleoplasm. Predicted to be part of U12-type spliceosomal complex. Orthologous to human SNRNP25 (small nuclear ribonucleoprotein U11/U12 subunit 25). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Liver (RPKM 280.4), Thymus (RPKM 110.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Snrnp25 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15924932..15928279, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (15420482..15423806, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15685999..15689338, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene N-methylpurine-DNA glycosylase Neighboring gene rhomboid 5 homolog 1 Neighboring gene interleukin 9 receptor Neighboring gene ribosomal protein S2, pseudogene 36

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Minor spliceosome components are predominantly localized in the nucleus. Pessa HK, et al. Proc Natl Acad Sci U S A, 2008 Jun 24. PMID 18559850, Free PMC Article
    2. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. Will CL, et al. RNA, 2004 Jun. PMID 15146077, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of U12-type spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U12-type spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in intercellular bridge ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    U11/U12 small nuclear ribonucleoprotein 25 kDa protein
    Names
    minus -99 protein
    small nuclear ribonucleoprotein 25 (U11/U12)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398566.1 → NP_001385495.1  U11/U12 small nuclear ribonucleoprotein 25 kDa protein

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A6HDB5, D3ZE11
      Conserved Domains (1) summary
      cd17058
      Location:31 → 119
      Ubl_SNRNP25; ubiquitin-like (Ubl) domain found in small nuclear ribonucleoprotein U11/U12 subunit 25 (SNRNP25) and similar proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      15924932..15928279 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039087123.2 → XP_038943051.1  U11/U12 small nuclear ribonucleoprotein 25 kDa protein isoform X4

    2. XM_063268571.1 → XP_063124641.1  U11/U12 small nuclear ribonucleoprotein 25 kDa protein isoform X3

    3. XM_006246078.4 → XP_006246140.1  U11/U12 small nuclear ribonucleoprotein 25 kDa protein isoform X2

      See identical proteins and their annotated locations for XP_006246140.1

    4. XM_008767620.3 → XP_008765842.1  U11/U12 small nuclear ribonucleoprotein 25 kDa protein isoform X1

      See identical proteins and their annotated locations for XP_008765842.1

    Nucleotide Protein Strain
    Heading Accession and Version

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