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    Armh4 armadillo-like helical domain containing 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361032, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Armh4provided by RGD
    Official Full Name
    armadillo-like helical domain containing 4provided by RGD
    Primary source
    RGD:1310110
    See related
    EnsemblRapid:ENSRNOG00000031849 AllianceGenome:RGD:1310110
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310110
    Summary
    Predicted to enable TORC2 complex binding activity. Predicted to be involved in regulation of TORC2 signaling and regulation of inflammatory response. Predicted to be located in membrane. Orthologous to human ARMH4 (armadillo like helical domain containing 4). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 146.6), Kidney (RPKM 16.8) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Armh4 in Genome Data Viewer
    Location:
    15p14
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (25455478..25556569, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (22975895..23076986, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (26586359..26687412, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 198 Neighboring gene solute carrier family 35, member F4 Neighboring gene uncharacterized LOC102556222 Neighboring gene transcription initiation factor IIA subunit 2-like Neighboring gene outer dynein arm docking complex subunit 2, pseudogene 1 Neighboring gene olfactory receptor family 4 subfamily N member 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables TORC2 complex binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of TORC2 signaling ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of inflammatory response ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    armadillo-like helical domain-containing protein 4
    Names
    uncharacterized protein C14orf37 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108374.1 → NP_001101844.1  armadillo-like helical domain-containing protein 4

      See identical proteins and their annotated locations for NP_001101844.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474040
      UniProtKB/TrEMBL
      A0A8I6GIE0, A6KE89, D3ZYI3
      Related
      ENSRNOP00000051182.6, ENSRNOT00000041420.7
      Conserved Domains (1) summary
      pfam15767
      Location:48 → 599
      DUF4696; Domain of unknown function (DUF4696)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      25455478..25556569 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039093475.1 → XP_038949403.1  armadillo-like helical domain-containing protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A8I6GIE0
      Related
      ENSRNOP00000089792.2, ENSRNOT00000106281.2
      Conserved Domains (1) summary
      pfam15767
      Location:48 → 602
      DUF4696; Domain of unknown function (DUF4696)
    Nucleotide Protein Strain
    Heading Accession and Version

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