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    Tmem161b transmembrane protein 161B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 309953, updated on 2-Nov-2024

    Summary

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    Symbol
    Tmem161bprovided by RGD
    Full Name
    transmembrane protein 161Bprovided by RGD
    Primary source
    RGD:1309660
    See related
    EnsemblRapid:ENSRNOG00000032414 AllianceGenome:RGD:1309660
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309660
    Summary
    Predicted to be involved in regulation of cardiac muscle cell action potential and regulation of heart rate. Predicted to be located in membrane. Orthologous to human TMEM161B (transmembrane protein 161B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Heart (RPKM 131.2), Kidney (RPKM 116.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem161b in Genome Data Viewer
    Location:
    2q11
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (16447094..16529359)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (14714451..14793809)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (12252522..12550368)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108349917 Neighboring gene stathmin like, pseudogene 4 Neighboring gene uncharacterized LOC102554306 Neighboring gene uncharacterized LOC120100661

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in regulation of cardiac muscle cell action potential ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of heart rate ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 161B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001433109.1 → NP_001420038.1  transmembrane protein 161B isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002

    2. NM_001433110.1 → NP_001420039.1  transmembrane protein 161B isoform b

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002

    3. NM_001433111.1 → NP_001420040.1  transmembrane protein 161B isoform c

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002

    4. NM_001433112.1 → NP_001420041.1  transmembrane protein 161B isoform d

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002

    5. NM_001433113.1 → NP_001420042.1  transmembrane protein 161B isoform e

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002

    6. NM_001433114.1 → NP_001420043.1  transmembrane protein 161B isoform e

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002

    7. NM_001433115.1 → NP_001420044.1  transmembrane protein 161B isoform e

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      16447094..16529359
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063282659.1 → XP_063138729.1  transmembrane protein 161B isoform X1

      UniProtKB/TrEMBL
      A0A8I5Y238
      Related
      ENSRNOP00000078226.1, ENSRNOT00000108171.2

    2. XM_063282668.1 → XP_063138738.1  transmembrane protein 161B isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZR74
      Related
      ENSRNOP00000049795.6, ENSRNOT00000050072.7

    3. XM_063282661.1 → XP_063138731.1  transmembrane protein 161B isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZR74
      Related
      ENSRNOP00000080669.1, ENSRNOT00000102942.2

    4. XM_063282667.1 → XP_063138737.1  transmembrane protein 161B isoform X6

    5. XM_039103416.2 → XP_038959344.1  transmembrane protein 161B isoform X7

      Conserved Domains (1) summary
      pfam10268
      Location:2 → 305
      Tmemb_161AB; Predicted transmembrane protein 161AB

    6. XM_063282673.1 → XP_063138743.1  transmembrane protein 161B isoform X9

    7. XM_063282662.1 → XP_063138732.1  transmembrane protein 161B isoform X4

    8. XM_063282672.1 → XP_063138742.1  transmembrane protein 161B isoform X8

    9. XM_063282665.1 → XP_063138735.1  transmembrane protein 161B isoform X5

    10. XM_063282663.1 → XP_063138733.1  transmembrane protein 161B isoform X5

    11. XM_063282660.1 → XP_063138730.1  transmembrane protein 161B isoform X2

      UniProtKB/TrEMBL
      A0A8I5Y238

    12. XM_063282666.1 → XP_063138736.1  transmembrane protein 161B isoform X5

    13. XM_063282664.1 → XP_063138734.1  transmembrane protein 161B isoform X5

    14. XM_063282669.1 → XP_063138739.1  transmembrane protein 161B isoform X8

    15. XM_063282671.1 → XP_063138741.1  transmembrane protein 161B isoform X8

    16. XM_063282670.1 → XP_063138740.1  transmembrane protein 161B isoform X8

    RNA

    1. XR_005500479.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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