Zfp112 zinc finger protein 112 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Zfp112provided by RGD
Official Full Name: zinc finger protein 112provided by RGD
Primary source: RGD:1305757
See related: EnsemblRapid:ENSRNOG00000029022 AllianceGenome:RGD:1305757
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF112 (zinc finger protein 112). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Brain (RPKM 22.2), Kidney (RPKM 15.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q21

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (88804833..88819889)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (79676933..79691994)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (80944118..80959072)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: zinc finger protein 112

Names: zinc finger protein 112 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001107487.1 → NP_001100957.1 zinc finger protein 112

See identical proteins and their annotated locations for NP_001100957.1

Status: PROVISIONAL

Source sequence(s)

CH473979

UniProtKB/TrEMBL

A0A0G2K9F8, A6J8W5

Related

ENSRNOP00000074981.2, ENSRNOT00000087253.3

Conserved Domains (5) summary

smart00349
Location:2 → 62

KRAB; krueppel associated box

COG5048
Location:508 → 852

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:539 → 559

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam01352
Location:2 → 41

KRAB; KRAB box

pfam13465
Location:523 → 548

zf-H2C2_2; Zinc-finger double domain