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    Crygs crystallin, gamma S [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689897, updated on 28-Oct-2024

    Summary

    Official Symbol
    Crygsprovided by RGD
    Official Full Name
    crystallin, gamma Sprovided by RGD
    Primary source
    RGD:1587483
    See related
    EnsemblRapid:ENSRNOG00000038355 AllianceGenome:RGD:1587483
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be a structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Predicted to act upstream of or within morphogenesis of an epithelium. Human ortholog(s) of this gene implicated in cataract 20 multiple types. Orthologous to human CRYGS (crystallin gamma S). [provided by Alliance of Genome Resources, Oct 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Expression
    Biased expression in Kidney (RPKM 3.0), Liver (RPKM 1.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Crygs in Genome Data Viewer
    Location:
    11q23
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (91711755..91716858)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (78207170..78212273)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (81796891..81802172)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member B11 Neighboring gene TBCC domain containing 1 Neighboring gene uncharacterized LOC100911962 Neighboring gene high mobility group nucleosomal binding domain 2, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    gamma-crystallin S
    Names
    beta-crystallin S
    gamma-S-crystallin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109553.1NP_001103023.1  gamma-crystallin S

      See identical proteins and their annotated locations for NP_001103023.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473999
      UniProtKB/Swiss-Prot
      P0C5E9
      UniProtKB/TrEMBL
      A6JS55
      Related
      ENSRNOP00000055204.2, ENSRNOT00000058402.4
      Conserved Domains (1) summary
      pfam00030
      Location:786
      Crystall; Beta/Gamma crystallin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      91711755..91716858
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063270770.1XP_063126840.1  gamma-crystallin S isoform X1