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    Phtf2 putative homeodomain transcription factor 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296762, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Phtf2provided by RGD
    Official Full Name
    putative homeodomain transcription factor 2provided by RGD
    Primary source
    RGD:1310593
    See related
    EnsemblRapid:ENSRNOG00000013517 AllianceGenome:RGD:1310593
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in endoplasmic reticulum. Orthologous to human PHTF2 (putative homeodomain transcription factor 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 233.6), Heart (RPKM 122.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Phtf2 in Genome Data Viewer
    Location:
    4q11
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (15107341..15222683)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (14215190..14330549)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (10823191..10938273)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486554 Neighboring gene round spermatid basic protein 1-like Neighboring gene Alu-mediated CDKN1A/p21 transcriptional regulator Neighboring gene transmembrane protein 60 Neighboring gene uncharacterized LOC120102478 Neighboring gene membrane associated guanylate kinase, WW and PDZ domain containing 2 Neighboring gene uncharacterized LOC120102477

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The novel testicular enrichment protein Cfap58 is required for Notch-associated ciliogenesis. Li ZZ, et al. Biosci Rep, 2020 Jan 31. PMID 31904090, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein PHTF2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106577.2 → NP_001100047.2  protein PHTF2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A6K5D0, D3ZSS0
      Related
      ENSRNOP00000059716.3, ENSRNOT00000066739.5
      Conserved Domains (1) summary
      pfam12129
      Location:5 → 154
      Phtf-FEM1B_bdg; Male germ-cell putative homeodomain transcription factor

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      15107341..15222683
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063285715.1 → XP_063141785.1  protein PHTF2 isoform X5

    2. XM_063285711.1 → XP_063141781.1  protein PHTF2 isoform X2

      Related
      ENSRNOP00000108919.1, ENSRNOT00000145889.1

    3. XM_063285710.1 → XP_063141780.1  protein PHTF2 isoform X1

      UniProtKB/TrEMBL
      D3ZSS0

    4. XM_063285713.1 → XP_063141783.1  protein PHTF2 isoform X3

    5. XM_063285714.1 → XP_063141784.1  protein PHTF2 isoform X3

    6. XM_063285712.1 → XP_063141782.1  protein PHTF2 isoform X3

    7. XM_063285709.1 → XP_063141779.1  protein PHTF2 isoform X1

      UniProtKB/TrEMBL
      D3ZSS0

    8. XM_039107250.2 → XP_038963178.1  protein PHTF2 isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version

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