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    Dynlt5 dynein light chain Tctex-type family member 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362553, updated on 2-Nov-2024

    Summary

    Official Symbol
    Dynlt5provided by RGD
    Official Full Name
    dynein light chain Tctex-type family member 5provided by RGD
    Primary source
    RGD:1311932
    See related
    EnsemblRapid:ENSRNOG00000023100 AllianceGenome:RGD:1311932
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tctex1d1; RGD1311932
    Summary
    Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Predicted to be part of cytoplasmic dynein complex. Predicted to be active in cytoplasm. Orthologous to human DYNLT5 (dynein light chain Tctex-type family member 5). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 40.7), Testes (RPKM 21.5) and 1 other tissue See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Dynlt5 in Genome Data Viewer
    Location:
    5q33
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (122964568..122987304)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (117735509..117758221)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (122498892..122522110)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 4B Neighboring gene uncharacterized LOC102548249 Neighboring gene uncharacterized LOC134486957 Neighboring gene SH3GL interacting endocytic adaptor 1 Neighboring gene small EDRK-rich factor 2 pseudogene Neighboring gene insulin like 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables dynein intermediate chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in microtubule-based movement IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytoplasmic dynein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    dynein light chain Tctex-type 5
    Names
    Tctex1 domain containing 1
    tctex1 domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135030.2NP_001128502.1  dynein light chain Tctex-type 5 isoform 1

      See identical proteins and their annotated locations for NP_001128502.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A6JRR8, D3Z8A1
      Related
      ENSRNOP00000036168.4, ENSRNOT00000038410.7
      Conserved Domains (1) summary
      pfam03645
      Location:75171
      Tctex-1; Tctex-1 family
    2. NM_001415953.1NP_001402882.1  dynein light chain Tctex-type 5 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A6JRS0

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      122964568..122987304
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006238459.5XP_006238521.1  dynein light chain Tctex-type 5 isoform X1

      See identical proteins and their annotated locations for XP_006238521.1

      UniProtKB/TrEMBL
      A0A8I6GJS0
      Related
      ENSRNOP00000092434.1, ENSRNOT00000099871.2
      Conserved Domains (1) summary
      pfam03645
      Location:80176
      Tctex-1; Tctex-1 family
    2. XM_008763889.4XP_008762111.1  dynein light chain Tctex-type 5 isoform X2

      See identical proteins and their annotated locations for XP_008762111.1

      UniProtKB/TrEMBL
      A6JRR8, D3Z8A1
      Conserved Domains (1) summary
      pfam03645
      Location:75171
      Tctex-1; Tctex-1 family