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    Prickle3 prickle planar cell polarity protein 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 317380, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Prickle3provided by RGD
    Official Full Name
    prickle planar cell polarity protein 3provided by RGD
    Primary source
    RGD:1359685
    See related
    EnsemblRapid:ENSRNOG00000022417 AllianceGenome:RGD:1359685
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be located in mitochondrion. Orthologous to human PRICKLE3 (prickle planar cell polarity protein 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 68.1), Heart (RPKM 65.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Prickle3 in Genome Data Viewer
    Location:
    Xq12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (17509551..17520157, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (14837647..14849305, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (15682652..15693473, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene G patch domain and KOW motifs Neighboring gene uncharacterized LOC134484177 Neighboring gene MAGI family member, X-linked Neighboring gene proteolipid protein 2 Neighboring gene synaptophysin Neighboring gene uncharacterized LOC120099258 Neighboring gene calcium voltage-gated channel subunit alpha1 F

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    prickle planar cell polarity protein 3
    Names
    LIM domain only 6
    prickle homolog 3
    prickle-like protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014110.1 → NP_001014132.1  prickle planar cell polarity protein 3

      See identical proteins and their annotated locations for NP_001014132.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085918
      UniProtKB/TrEMBL
      A0A8I5ZZA9, F1LPT2, Q5U2Q0
      Related
      ENSRNOP00000013758.6, ENSRNOT00000013758.8
      Conserved Domains (4) summary
      cd09415
      Location:186 → 244
      LIM1_Prickle; The first LIM domain of Prickle
      cd09418
      Location:249 → 304
      LIM2_Prickle; The second LIM domain of Prickle
      cd09420
      Location:309 → 367
      LIM3_Prickle; The third LIM domain of Prickle
      cd09827
      Location:82 → 178
      PET_Prickle; The PET domain of Prickle

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      17509551..17520157 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039099792.2 → XP_038955720.1  prickle planar cell polarity protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZZA9
      Conserved Domains (4) summary
      cd09415
      Location:118 → 176
      LIM1_Prickle; The first LIM domain of Prickle
      cd09418
      Location:181 → 236
      LIM2_Prickle; The second LIM domain of Prickle
      cd09420
      Location:241 → 299
      LIM3_Prickle; The third LIM domain of Prickle
      cd09827
      Location:14 → 110
      PET_Prickle; The PET domain of Prickle

    2. XM_039099791.2 → XP_038955719.1  prickle planar cell polarity protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZZA9
      Conserved Domains (4) summary
      cd09415
      Location:118 → 176
      LIM1_Prickle; The first LIM domain of Prickle
      cd09418
      Location:181 → 236
      LIM2_Prickle; The second LIM domain of Prickle
      cd09420
      Location:241 → 299
      LIM3_Prickle; The third LIM domain of Prickle
      cd09827
      Location:14 → 110
      PET_Prickle; The PET domain of Prickle
    Nucleotide Protein Strain
    Heading Accession and Version

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