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    Zmym5 zinc finger MYM-type containing 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305911, updated on 10-Oct-2024

    Summary

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    Official Symbol
    Zmym5provided by RGD
    Official Full Name
    zinc finger MYM-type containing 5provided by RGD
    Primary source
    RGD:1306353
    See related
    EnsemblRapid:ENSRNOG00000029220 AllianceGenome:RGD:1306353
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306353
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Orthologous to human ZMYM5 (zinc finger MYM-type containing 5). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Lung (RPKM 163.6), Thymus (RPKM 152.2) and 9 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zmym5 in Genome Data Viewer
    Location:
    15p12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (35036226..35056842, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (30920479..30941249, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (37039481..37061958, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA5 Neighboring gene M-phase phosphoprotein 8 Neighboring gene paraspeckle component 1 Neighboring gene ribosomal protein L39, pseudogene 4 Neighboring gene ribosomal protein L26, pseudogene 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Analysis of transcriptional modulation of the presenilin 1 gene promoter by ZNF237, a candidate binding partner of the Ets transcription factor ERM. Pastorcic M, et al. Brain Res, 2007 Jan 12. PMID 17126306, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger MYM-type containing 5; zinc finger MYM-type protein 5
    Names
    zinc finger, MYM-type 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001433028.1 → NP_001419957.1  zinc finger MYM-type containing 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      A6KHA6, D3ZPX0

    2. NM_001433029.1 → NP_001419958.1  zinc finger MYM-type containing 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      A6KHA6, D3ZPX0

    3. NM_001433030.1 → NP_001419959.1  zinc finger MYM-type containing 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      A6KHA6, D3ZPX0

    4. NM_001433031.1 → NP_001419960.1  zinc finger MYM-type containing 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      A6KHA6, D3ZPX0

    5. NM_001433032.1 → NP_001419961.1  zinc finger MYM-type containing 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      A6KHA6, D3ZPX0

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      35036226..35056842 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039093849.2 → XP_038949777.1  zinc finger MYM-type protein 5

      Conserved Domains (3) summary
      smart00597
      Location:529 → 596
      ZnF_TTF; zinc finger in transposases and transcription factors
      smart00746
      Location:214 → 250
      TRASH; metallochaperone-like domain
      pfam06467
      Location:344 → 382
      zf-FCS; MYM-type Zinc finger with FCS sequence motif

    2. XM_039093850.2 → XP_038949778.1  zinc finger MYM-type protein 5

      Conserved Domains (3) summary
      smart00597
      Location:529 → 596
      ZnF_TTF; zinc finger in transposases and transcription factors
      smart00746
      Location:214 → 250
      TRASH; metallochaperone-like domain
      pfam06467
      Location:344 → 382
      zf-FCS; MYM-type Zinc finger with FCS sequence motif

    3. XM_039093852.2 → XP_038949780.1  zinc finger MYM-type protein 5

      UniProtKB/TrEMBL
      A6KHA6, D3ZPX0
      Conserved Domains (3) summary
      smart00597
      Location:529 → 596
      ZnF_TTF; zinc finger in transposases and transcription factors
      smart00746
      Location:214 → 250
      TRASH; metallochaperone-like domain
      pfam06467
      Location:344 → 382
      zf-FCS; MYM-type Zinc finger with FCS sequence motif

    4. XM_063274864.1 → XP_063130934.1  zinc finger MYM-type protein 5

      Related
      ENSRNOP00000041172.3, ENSRNOT00000047731.6

    5. XM_006252083.5 → XP_006252145.1  zinc finger MYM-type protein 5

      Conserved Domains (3) summary
      smart00597
      Location:529 → 596
      ZnF_TTF; zinc finger in transposases and transcription factors
      smart00746
      Location:214 → 250
      TRASH; metallochaperone-like domain
      pfam06467
      Location:344 → 382
      zf-FCS; MYM-type Zinc finger with FCS sequence motif

    6. XM_063274865.1 → XP_063130935.1  zinc finger MYM-type protein 5

    7. XM_063274866.1 → XP_063130936.1  zinc finger MYM-type protein 5

      UniProtKB/TrEMBL
      A6KHA6, D3ZPX0
    Nucleotide Protein Strain
    Heading Accession and Version

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