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    RSA-14-44 RSA-14-44 protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297173, updated on 10-Jul-2024

    Summary

    Symbol
    RSA-14-44provided by RGD
    Full Name
    RSA-14-44 proteinprovided by RGD
    Primary source
    RGD:735071
    See related
    EnsemblRapid:ENSRNOG00000042954 AllianceGenome:RGD:735071
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including cytoskeleton organization; regulation of actin cytoskeleton organization; and regulation of cell shape. Predicted to be active in several cellular components, including cell cortex; cleavage furrow; and dendritic spine. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See RSA-14-44 in Genome Data Viewer
    Location:
    4q31
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (96581411..96582783)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (95251657..95253029)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (96831880..96833252)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene transfer RNA leucine (anticodon AAG) 20 Neighboring gene PR/SET domain 5 Neighboring gene U6 spliceosomal RNA Neighboring gene lin-28 homolog C (C. elegans)

    Genomic regions, transcripts, and products

    General gene information

    Clone Names

    • MGC94489

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in Rho protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in stress fiber assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cleavage furrow IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in dendritic spine IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ras homolog gene family, member A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_182670.2NP_872611.2  ras homolog gene family, member A

      See identical proteins and their annotated locations for NP_872611.2

      Status: VALIDATED

      Source sequence(s)
      BC083656, CK603687
      UniProtKB/TrEMBL
      A6KF31, F7FGN9, Q5XIM3, Q80WN4
      Related
      ENSRNOP00000061832.1, ENSRNOT00000068400.5
      Conserved Domains (1) summary
      cd01870
      Location:5179
      RhoA_like; Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      96581411..96582783
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)