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    IRS2 insulin receptor substrate 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698536, updated on 17-Aug-2024

    Summary

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    Official Symbol
    IRS2provided by VGNC
    Official Full Name
    insulin receptor substrate 2provided by VGNC
    Primary source
    VGNC:VGNC:82164
    See related
    Ensembl:ENSMMUG00000021790
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See IRS2 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 17 NC_041770.1 (91225001..91256008, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 17 NC_027909.1 (91452094..91482445, complement)

    Chromosome 17 - NC_041770.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106994389 Neighboring gene uncharacterized LOC114673586 Neighboring gene uncharacterized LOC106994377 Neighboring gene uncharacterized LOC114673476

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables insulin receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol 3-kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in insulin receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    insulin receptor substrate 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041770.1 Reference Mmul_10 Primary Assembly

      Range
      91225001..91256008 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002800838.3 → XP_002800884.2  insulin receptor substrate 2

      UniProtKB/TrEMBL
      A0A5F7ZUJ1, F7DE94
      Related
      ENSMMUP00000069329.1, ENSMMUT00000087451.1
      Conserved Domains (3) summary
      cd01204
      Location:191 → 294
      PTB_IRS; Insulin receptor substrate phosphotyrosine-binding domain (PTBi)
      cd01257
      Location:31 → 147
      PH_IRS; Insulin receptor substrate (IRS) pleckstrin homology (PH) domain
      pfam00169
      Location:31 → 144
      PH; PH domain
    Nucleotide Protein
    Heading Accession and Version

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