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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029376.2 RefSeqGene
- Range
-
5001..21524
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_1311
mRNA and Protein(s)
-
NM_001203263.2 → NP_001190192.2 interleukin-17 receptor C isoform 4 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks the penultimate coding exon compared to variant 1, however, maintains the reading frame. This results in a shorter isoform (4) missing a protein segment in the C-terminal region compared to isoform 1.
- Source sequence(s)
-
AC018809
- Consensus CDS
-
CCDS56240.1
- UniProtKB/TrEMBL
-
A0A8Q3SJ19
- Related
- ENSP00000396064.1, ENST00000413608.2
- Conserved Domains (2) summary
-
- pfam08357
Location:506 → 653
- SEFIR; SEFIR domain
- pfam15037
Location:71 → 459
- IL17_R_N; Interleukin-17 receptor extracellular region
-
NM_001203264.2 → NP_001190193.2 interleukin-17 receptor C isoform 5 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks 2 in-frame coding exons (exon 12 and penultimate exon) compared to variant 1, resulting in a shorter isoform (5, also known as IL-17RCdelta12) missing 2 internal protein segments compared to isoform 1. It has been reported that isoforms lacking exon 12 lose the ability to bind cytokines, IL-17A and IL-17F (PMID:17911633).
- Source sequence(s)
-
AC018809
- Consensus CDS
-
CCDS74898.1
- UniProtKB/TrEMBL
-
A0A8Q3SIU5
- Related
- ENSP00000395315.3, ENST00000416074.6
- Conserved Domains (3) summary
-
- pfam08357
Location:489 → 636
- SEFIR; SEFIR domain
- pfam15037
Location:71 → 442
- IL17_R_N; Interleukin-17 receptor extracellular region
- pfam17243
Location:632 → 668
- POTRA_TamA_1; POTRA domain TamA domain 1
-
NM_001203265.2 → NP_001190194.2 interleukin-17 receptor C isoform 6 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) lacks 2 in-frame coding exons (exons 7 and 12) compared to variant 1, resulting in a shorter isoform (6, also known as IL-17RCdelta7,12) missing 2 internal protein segments compared to isoform 1. It has been reported that isoforms lacking exon 12 lose the ability to bind cytokines, IL-17A and IL-17F (PMID:17911633).
- Source sequence(s)
-
AC018809
- Consensus CDS
-
CCDS56241.1
- UniProtKB/TrEMBL
-
A0A8Q3SIU5
- Related
- ENSP00000407894.1, ENST00000455057.5
- Conserved Domains (2) summary
-
- pfam08357
Location:487 → 634
- SEFIR; SEFIR domain
- pfam15037
Location:71 → 427
- IL17_R_N; Interleukin-17 receptor extracellular region
-
NM_001367278.1 → NP_001354207.1 interleukin-17 receptor C isoform 7 precursor
Status: REVIEWED
- Source sequence(s)
-
AC018809
- Consensus CDS
-
CCDS93201.1
- UniProtKB/TrEMBL
- A0A8Q3SIV5, A0A8Q3SJJ9
- Related
- ENSP00000512902.1, ENST00000696824.1
- Conserved Domains (2) summary
-
- pfam08357
Location:493 → 640
- SEFIR; SEFIR domain
- pfam15037
Location:71 → 446
- IL17_R_N; Interleukin-17 receptor extracellular region
-
NM_001367279.1 → NP_001354208.1 interleukin-17 receptor C isoform 8 precursor
Status: REVIEWED
- Source sequence(s)
-
AC018809
- UniProtKB/TrEMBL
-
A0A8Q3WM30
- Conserved Domains (2) summary
-
- pfam08357
Location:466 → 613
- SEFIR; SEFIR domain
- pfam15037
Location:71 → 419
- IL17_R_N; Interleukin-17 receptor extracellular region
-
NM_001367280.1 → NP_001354209.1 interleukin-17 receptor C isoform 9 precursor
Status: REVIEWED
- Source sequence(s)
-
AC018809
- Consensus CDS
-
CCDS93202.1
- UniProtKB/TrEMBL
-
A0A8Q3SJ19
- Related
- ENSP00000512897.1, ENST00000696816.1
- Conserved Domains (2) summary
-
- pfam08357
Location:491 → 638
- SEFIR; SEFIR domain
- pfam15037
Location:71 → 444
- IL17_R_N; Interleukin-17 receptor extracellular region
-
NM_001410711.1 → NP_001397640.1 interleukin-17 receptor C isoform 10 precursor
Status: REVIEWED
- Source sequence(s)
-
AC018809
- Consensus CDS
-
CCDS93203.1
- UniProtKB/TrEMBL
-
A0A8Q3SJ01
- Related
- ENSP00000512904.1, ENST00000696826.1
-
NM_032732.6 → NP_116121.3 interleukin-17 receptor C isoform 3 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an in-frame coding exon (exon 7) compared to variant 1, resulting in a shorter isoform (3, also known as IL-17RCdelta7) missing an internal protein segment compared to isoform 1. It has been reported that isoform lacking exon 7 retains the ability to bind cytokines, IL-17A and IL-17F (PMID:17911633).
- Source sequence(s)
-
AC018809
- Consensus CDS
-
CCDS2591.2
- UniProtKB/TrEMBL
-
A0A8Q3SJ19
- Related
- ENSP00000373323.4, ENST00000383812.9
- Conserved Domains (2) summary
-
- pfam08357
Location:504 → 651
- SEFIR; SEFIR domain
- pfam15037
Location:71 → 444
- IL17_R_N; Interleukin-17 receptor extracellular region
-
NM_153460.4 → NP_703190.2 interleukin-17 receptor C isoform 1 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the predominant transcript containing all the coding exons, and encodes isoform 1 (also known as IL-17RCFL).
- Source sequence(s)
-
AC018809, AF458065, AK096824, AK225650, AY358840, DC381087
- Consensus CDS
-
CCDS46746.1
- UniProtKB/TrEMBL
-
A0A8Q3SJ19
- Related
- ENSP00000384969.3, ENST00000403601.8
- Conserved Domains (2) summary
-
- pfam08357
Location:519 → 666
- SEFIR; SEFIR domain
- pfam15037
Location:71 → 459
- IL17_R_N; Interleukin-17 receptor extracellular region
-
NM_153461.4 → NP_703191.2 interleukin-17 receptor C isoform 2 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate donor splice site at the 5' terminal coding exon compared to variant 1, resulting in a longer isoform (2) containing an additional protein segment compared to isoform 1.
- Source sequence(s)
-
AC018809
- Consensus CDS
-
CCDS2590.1
- UniProtKB/Swiss-Prot
- A8BWC1, A8BWC9, A8BWD5, E9PHG1, E9PHJ6, Q6UVY3, Q6UWD4, Q8NAC3, Q8NFS1, Q9BR97
- UniProtKB/TrEMBL
-
A0A8Q3SJ19
- Related
- ENSP00000295981.3, ENST00000295981.7
- Conserved Domains (2) summary
-
- pfam08357
Location:590 → 737
- SEFIR; SEFIR domain
- pfam15037
Location:142 → 530
- IL17_R_N; Interleukin-17 receptor extracellular region
RNA
-
NR_037807.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) lacks exon 7 and is alternatively spliced in the mid-coding region compared to variant 1. It is represented as non-coding because the use of the 5'-most translational start codon as used in variant 1, renders this transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC018809
- Related
-
ENST00000466046.5
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_153462.1: Suppressed sequence
- Description
- NM_153462.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein, and because it is a nonsense-mediated mRNA decay (NMD) candidate.
-
NM_153463.1: Suppressed sequence
- Description
- NM_153463.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.