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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001284330.2 → NP_001271259.1 DNA-directed DNA/RNA polymerase mu isoform 2
See identical proteins and their annotated locations for NP_001271259.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) has multiple differences in the coding region, compared to variant 1, one of which results in a translational frameshift, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus and is longer than isoform 1.
- Source sequence(s)
-
AA917987, AU309799, BC049202
- Consensus CDS
-
CCDS64636.1
- UniProtKB/Swiss-Prot
-
Q9NP87
- Related
- ENSP00000379174.3, ENST00000395831.7
- Conserved Domains (3) summary
-
- smart00483
Location:152 → 383
- POLXc; DNA polymerase X family
- cd00027
Location:29 → 109
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
- cl11966
Location:156 → 387
- NT_Pol-beta-like; Nucleotidyltransferase (NT) domain of DNA polymerase beta and similar proteins
-
NM_001284331.2 → NP_001271260.1 DNA-directed DNA/RNA polymerase mu isoform 3
See identical proteins and their annotated locations for NP_001271260.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This results in a isoform (3) that is shorter, compared to isoform 1.
- Source sequence(s)
-
AA917987, AU309799, BC062590
- Consensus CDS
-
CCDS64635.1
- UniProtKB/Swiss-Prot
-
Q9NP87
- Related
- ENSP00000335141.6, ENST00000335195.10
- Conserved Domains (3) summary
-
- cd00141
Location:156 → 455
- NT_POLXc; Nucleotidyltransferase (NT) domain of family X DNA Polymerases
- smart00483
Location:152 → 456
- POLXc; DNA polymerase X family
- cd00027
Location:29 → 109
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
-
NM_001362683.2 → NP_001349612.1 DNA-directed DNA/RNA polymerase mu isoform 4
Status: VALIDATED
- Source sequence(s)
-
AA917987, AF176097, AU309799, BM744180, BM756419
- Conserved Domains (2) summary
-
- cd00141
Location:156 → 467
- NT_POLXc; Nucleotidyltransferase (NT) domain of family X DNA Polymerases
- cd00027
Location:29 → 109
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
-
NM_013284.4 → NP_037416.1 DNA-directed DNA/RNA polymerase mu isoform 1
See identical proteins and their annotated locations for NP_037416.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes isoform 1.
- Source sequence(s)
-
AA917987, AF176097, AU309799
- Consensus CDS
-
CCDS34625.1
- UniProtKB/Swiss-Prot
- D3DVK4, Q6P5X8, Q86WQ9, Q9NP87
- Related
- ENSP00000242248.5, ENST00000242248.10
- Conserved Domains (3) summary
-
- cd00141
Location:156 → 492
- NT_POLXc; Nucleotidyltransferase (NT) domain of family X DNA Polymerases
- smart00483
Location:152 → 493
- POLXc; DNA polymerase X family
- cd00027
Location:29 → 109
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
RNA
-
NR_104299.2 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) uses two alternate splice sites, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AA917987, AC017116, AK023002, AU309799
- Related
-
ENST00000430942.5
-
NR_156112.2 RNA Sequence
Status: VALIDATED
- Source sequence(s)
-
AA917987, AC017116, AF176097, AU309799, BC049202, BX395027
-
NR_156113.2 RNA Sequence
Status: VALIDATED
- Source sequence(s)
-
AA917987, AU309799, BC049202, BG386713, BX395027
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000007.14 Reference GRCh38.p14 Primary Assembly
- Range
-
44072062..44082530 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060931.1 Alternate T2T-CHM13v2.0
- Range
-
44230561..44241032 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)