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    LUZP6 leucine zipper protein 6 [ Homo sapiens (human) ]

    Gene ID: 767558, updated on 17-Sep-2024

    Summary

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    Official Symbol
    LUZP6provided by HGNC
    Official Full Name
    leucine zipper protein 6provided by HGNC
    Primary source
    HGNC:HGNC:33955
    See related
    MIM:611050; AllianceGenome:HGNC:33955
    Gene type
    unknown
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MPD6; MTPNUT
    Annotation information
    not in current annotation release
    Expression
    Ubiquitous expression in brain (RPKM 74.6), esophagus (RPKM 68.4) and 24 other tissues See more
    Orthologs
    all

    Genomic context

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    See LUZP6 in Genome Data Viewer
    Location:
    7q33
    Annotation release Status Assembly Chr Location
    109.20211119 latest, but not current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (135926760..135928972, complement)

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. A Circulating Exosome RNA Signature Is a Potential Diagnostic Marker for Pancreatic Cancer, a Systematic Study. Wu Y, et al. Cancers (Basel), 2021 May 24. PMID 34073722, Free PMC Article
    2. An unconventional antigen translated by a novel internal ribosome entry site elicits antitumor humoral immune reactions. Xiong Z, et al. J Immunol, 2006 Oct 1. PMID 16982933, Free PMC Article
    3. Assessment of ApoC1, LuzP6, C12orf75 and OCC-1 in cystic glioblastoma using MALDI-TOF mass spectrometry, immunohistochemistry and qRT-PCR. Evangelou P, et al. Med Mol Morphol, 2019 Dec. PMID 31006040, Free PMC Article
    4. High-throughput analyses of hnRNP H1 dissects its multi-functional aspect. Uren PJ, et al. RNA Biol, 2016. PMID 26760575, Free PMC Article
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A 6.4 kDa tumor antigen is produced from a cryptic ORF in the 3' UTR of the MTPN gene by using a novel internal ribosome entry site and non-AUG translation initiation.
      Title: An unconventional antigen translated by a novel internal ribosome entry site elicits antitumor humoral immune reactions.
    Submit: New GeneRIF Correction

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Other Names

    • myeloproliferative disease-associated 6 kDa antigen
    • myeloproliferative disease-associated SEREX antigen
    • myeloproliferative disease-associated antigen, 6-kD
    • myotrophin 3'UTR transcript

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001128619.3: Suppressed sequence

      Description
      NM_001128619.3: This RefSeq was removed because it is now thought that this gene does not encode a protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q538Z0.1 GenPept UniProtKB/Swiss-Prot:Q538Z0

    Gene LinkOut

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