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    Zfp617 zinc finger protein 617 [ Mus musculus (house mouse) ]

    Gene ID: 170938, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Zfp617provided by MGI
    Official Full Name
    zinc finger protein 617provided by MGI
    Primary source
    MGI:MGI:2684459
    See related
    Ensembl:ENSMUSG00000066880 AllianceGenome:MGI:2684459
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zfps11-6
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human ZNF878 (zinc finger protein 878). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 7.8), bladder adult (RPKM 7.1) and 26 other tissues See more
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    Genomic context

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    See Zfp617 in Genome Data Viewer
    Location:
    8 B3.3; 8 34.59 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (72676669..72688474)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (71922825..71934630)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 709 Neighboring gene STARR-seq mESC enhancer starr_21833 Neighboring gene zinc finger protein 882 Neighboring gene STARR-positive B cell enhancer ABC_E10511 Neighboring gene cyclin B2, pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E3784 Neighboring gene STARR-seq mESC enhancer starr_21836 Neighboring gene zinc finger protein 961 Neighboring gene STARR-seq mESC enhancer starr_21837 Neighboring gene STARR-seq mESC enhancer starr_21838 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 18 Neighboring gene predicted gene, 51535

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The mouse genome: experimental examination of gene predictions and transcriptional start sites. Dike S, et al. Genome Res, 2004 Dec. PMID 15574821, Free PMC Article
    2. Genetic and structural analysis of the basolateral amygdala complex in BXD recombinant inbred mice. Mozhui K, et al. Behav Genet, 2007 Jan. PMID 17131200
    3. Identification of candidate lung cancer susceptibility genes in mouse using oligonucleotide arrays. Lemon WJ, et al. J Med Genet, 2002 Sep. PMID 12205107, Free PMC Article
    4. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
    5. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 617
    Names
    Zinc finger protein s11-6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133358.3 → NP_579936.2  zinc finger protein 617

      See identical proteins and their annotated locations for NP_579936.2

      Status: VALIDATED

      Source sequence(s)
      AK146644, BC014712, BX519071, CV307576
      Consensus CDS
      CCDS52590.1
      UniProtKB/TrEMBL
      Q91WM0
      Related
      ENSMUSP00000112926.2, ENSMUST00000119003.2
      Conserved Domains (5) summary
      smart00349
      Location:4 → 47
      KRAB; krueppel associated box
      COG5048
      Location:156 → 542
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:365 → 385
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 40
      KRAB; KRAB box
      pfam13465
      Location:461 → 486
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      72676669..72688474
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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