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    C36B7.6 Cleft lip and palate transmembrane protein 1 homolog [ Caenorhabditis elegans ]

    Gene ID: 180976, updated on 2-Nov-2024

    Summary

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    Official Symbol
    C36B7.6
    Official Full Name
    Cleft lip and palate transmembrane protein 1 homolog
    Primary source
    WormBase:WBGene00016469
    Locus tag
    CELE_C36B7.6
    See related
    AllianceGenome:WB:WBGene00016469
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be active in endomembrane system and membrane. Orthologous to human CLPTM1 (CLPTM1 regulator of GABA type A receptor forward trafficking). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See C36B7.6 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    10
    Sequence:
    Chromosome: X; NC_003284.9 (7096745..7100338, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene Apple domain-containing protein Neighboring gene Secreted protein Neighboring gene Protein kinase domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. Shen X, et al. PLoS Genet, 2005 Sep. PMID 16184190, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    acts_upstream_of_or_within IRE1-mediated unfolded protein response HEP PubMed 
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cleft lip and palate transmembrane protein 1 homolog
    NP_509196.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      7096745..7100338 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076795.5 → NP_509196.2  Cleft lip and palate transmembrane protein 1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509196.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q966P8
      Conserved Domains (1) summary
      pfam05602
      Location:32 → 466
      CLPTM1; Cleft lip and palate transmembrane protein 1 (CLPTM1)
    Nucleotide Protein
    Heading Accession and Version

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