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    ZK1127.5 putative RNA 3'-terminal phosphate cyclase-like protein [ Caenorhabditis elegans ]

    Gene ID: 174151, updated on 2-Nov-2024

    Summary

    Official Symbol
    ZK1127.5
    Official Full Name
    putative RNA 3'-terminal phosphate cyclase-like protein
    Primary source
    WormBase:WBGene00022852
    Locus tag
    CELE_ZK1127.5
    See related
    AllianceGenome:WB:WBGene00022852
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA endonuclease activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and ribosomal small subunit biogenesis. Predicted to be located in nucleus. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Is expressed in intestine and rectal gland cell. Orthologous to human RCL1 (RNA terminal phosphate cyclase like 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See ZK1127.5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (7050672..7051983)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Transcription elongation regulator 1;WW domain-containing protein Neighboring gene TIGR04255 family protein Neighboring gene Phage tail protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA endonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal small subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of small-subunit processome ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    putative RNA 3'-terminal phosphate cyclase-like protein
    NP_495445.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7050672..7051983
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063044.7NP_495445.2  putative RNA 3'-terminal phosphate cyclase-like protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495445.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q23400
      Conserved Domains (2) summary
      cd00875
      Location:2342
      RNA_Cyclase_Class_I; RNA 3' phosphate cyclase domain (class I) This subfamily of cyclase-like proteins are encoded in eukaryotic genomes. They lack a conserved catalytic histidine residue required for cyclase activity, so probably do not function as cyclases. They are ...
      TIGR03400
      Location:6378
      18S_RNA_Rcl1p; 18S rRNA biogenesis protein RCL1