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    Igsf6 immunoglobulin superfamily, member 6 [ Mus musculus (house mouse) ]

    Gene ID: 80719, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Igsf6provided by MGI
    Official Full Name
    immunoglobulin superfamily, member 6provided by MGI
    Primary source
    MGI:MGI:1891393
    See related
    Ensembl:ENSMUSG00000035004 AllianceGenome:MGI:1891393
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be located in membrane. Orthologous to human IGSF6 (immunoglobulin superfamily member 6). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in liver E18 (RPKM 6.0), liver E14 (RPKM 3.2) and 19 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Igsf6 in Genome Data Viewer
    Location:
    7 F2; 7 65.07 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (120663290..120673753, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (121064067..121074581, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene methyltransferase like 9 Neighboring gene predicted gene, 27991 Neighboring gene 60S ribosomal protein L32 pseudogene Neighboring gene otoancorin Neighboring gene STARR-seq mESC enhancer starr_20059 Neighboring gene src family associated phosphoprotein 2 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Characterization of the human PAP1 gene and its homologue possible involvement in mouse embryonic development. Shu KX, et al. Colloids Surf B Biointerfaces, 2006 Sep 1. PMID 16837177
    2. The mouse and human IGSF6 (DORA) genes map to the inflammatory bowel disease 1 locus and are embedded in an intron of a gene of unknown function. Bates EE, et al. Immunogenetics, 2000 Nov. PMID 11132146
    3. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
    4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    5. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    immunoglobulin superfamily member 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030691.1 → NP_109616.1  immunoglobulin superfamily member 6 precursor

      See identical proteins and their annotated locations for NP_109616.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ278575
      Consensus CDS
      CCDS21801.1
      UniProtKB/Swiss-Prot
      P0C6B7
      Related
      ENSMUSP00000039059.3, ENSMUST00000047194.4
      Conserved Domains (2) summary
      smart00410
      Location:35 → 141
      IG_like; Immunoglobulin like
      cl11960
      Location:35 → 142
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      120663290..120673753 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C6B7.1 GenPept UniProtKB/Swiss-Prot:P0C6B7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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