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    Cryzl2 crystallin zeta like 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 289138, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Cryzl2provided by RGD
    Official Full Name
    crystallin zeta like 2provided by RGD
    Primary source
    RGD:1304982
    See related
    Ensembl:ENSRNOG00000005177 AllianceGenome:RGD:1304982
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tp53i3; RGD1304982
    Summary
    Predicted to enable several functions, including NADPH binding activity; NADPH:quinone reductase activity; and protein homodimerization activity. Predicted to be involved in NADP metabolic process. Orthologous to human TP53I3 (tumor protein p53 inducible protein 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 219.5), Heart (RPKM 209.4) and 9 other tissues See more
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    Genomic context

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    See Cryzl2 in Genome Data Viewer
    Location:
    13q22
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (72146147..72210258)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (69612605..69655018)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (75101759..75145967)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2810025M15 gene like Neighboring gene uncharacterized LOC134481518 Neighboring gene ATP synthase F(0) complex subunit C2, mitochondrial-like Neighboring gene SEC16 homolog B, endoplasmic reticulum export factor Neighboring gene small nucleolar RNA SNORA48 Neighboring gene uncharacterized LOC120096293 Neighboring gene large ribosomal subunit protein eL28-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3. Porté S, et al. J Biol Chem, 2009 Jun 19. PMID 19349281, Free PMC Article
    2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    quinone oxidoreductase-like protein 2
    Names
    tumor protein p53 inducible protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001401440.1 → NP_001388369.1  quinone oxidoreductase-like protein 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000013
      UniProtKB/Swiss-Prot
      B0BNC9
      UniProtKB/TrEMBL
      A0A8I5ZMC2
      Related
      ENSRNOP00000006924.4, ENSRNOT00000006924.8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      72146147..72210258
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039090480.2 → XP_038946408.1  quinone oxidoreductase-like protein 2 isoform X6

      Conserved Domains (1) summary
      cl16912
      Location:102 → 259
      MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

    2. XM_039090474.2 → XP_038946402.1  quinone oxidoreductase-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZMC2
      Conserved Domains (1) summary
      cd08241
      Location:12 → 332
      QOR1; Quinone oxidoreductase (QOR)

    3. XM_039090476.2 → XP_038946404.1  quinone oxidoreductase-like protein 2 isoform X3

      UniProtKB/TrEMBL
      A6ID28
      Conserved Domains (1) summary
      cd08241
      Location:25 → 280
      QOR1; Quinone oxidoreductase (QOR)

    4. XM_039090481.2 → XP_038946409.1  quinone oxidoreductase-like protein 2 isoform X7

      UniProtKB/TrEMBL
      A6ID28
      Conserved Domains (1) summary
      cd08241
      Location:36 → 258
      QOR1; Quinone oxidoreductase (QOR)

    5. XM_039090483.2 → XP_038946411.1  quinone oxidoreductase-like protein 2 isoform X9

      Conserved Domains (1) summary
      cl16912
      Location:86 → 243
      MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

    6. XM_039090482.2 → XP_038946410.1  quinone oxidoreductase-like protein 2 isoform X8

      Conserved Domains (1) summary
      cl16912
      Location:92 → 249
      MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

    7. XM_039090484.2 → XP_038946412.1  quinone oxidoreductase-like protein 2 isoform X10

      UniProtKB/TrEMBL
      A0A8I6ASM8
      Related
      ENSRNOP00000097423.1
      Conserved Domains (1) summary
      cl16912
      Location:27 → 164
      MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

    8. XM_039090475.2 → XP_038946403.1  quinone oxidoreductase-like protein 2 isoform X2

      UniProtKB/TrEMBL
      A6ID28
      Conserved Domains (1) summary
      cd08241
      Location:40 → 295
      QOR1; Quinone oxidoreductase (QOR)

    9. XM_039090477.2 → XP_038946405.1  quinone oxidoreductase-like protein 2 isoform X4

      UniProtKB/TrEMBL
      A6ID28
      Conserved Domains (1) summary
      cd08241
      Location:51 → 273
      QOR1; Quinone oxidoreductase (QOR)

    10. XM_039090478.2 → XP_038946406.1  quinone oxidoreductase-like protein 2 isoform X5

      UniProtKB/TrEMBL
      A6ID28
      Conserved Domains (1) summary
      cd08241
      Location:26 → 271
      QOR1; Quinone oxidoreductase (QOR)

    RNA

    1. XR_005492221.2 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001113775.1: Suppressed sequence

      Description
      NM_001113775.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B0BNC9.1 GenPept UniProtKB/Swiss-Prot:B0BNC9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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